VenaSeal is considered very safe, and side effects are usually mild.
It's possible to have some bruising, swelling, and pain in the treated area, but many patients don't experience this. Unlike other sclerotherapy treatment options, such as radiofrequency ablation or endovenous laser, the VenaSeal closure system procedure is an entirely non-thermal procedure, so there's less bruising and pain associated with VenaSeal than with other treatment options for venous diseases.
There's also a lower risk of chemical irritation with VenaSeal than with a chemical sclerotherapy treatment like Varithena, though it is possible to have an allergic reaction to the glue.Â
Other possible risks include bleeding at the access site, hyperpigmentation, infection, phlebitis, vascular rupture, and visible scarring. Very rarely, patients experience deep vein thrombosis (DVT) and pulmonary embolism (PE). Talk with your vein specialist about these risks and how they mitigate them.