Will Hyaluronidase Dissolve Radiesse.

Unfortunately Radiesse cannot be dissolved with Vitrase / hyaluronidase. A combination of fractional laser or radiofrequency, Venus Legacy treatments, and 5FU/steroid injections could help reverse the results. Otherwise, aside from waiting to see if it goes away, the only other permanent option is surgical removal. I suggest getting a formal evaluation with a cosmetic dermatologist. Best, Dr. Emer.

Radiesse is an FDA-Approved filler that we use very frequently in our office to sculpt the contours of the face. Since we are a national center of excellence for filler reversal, we also encounter patients from other doctors' offices who wish to have Radiesse fillers removed for one reason or another. In our office, we employ a directed technique to visualize the filler material, if possible on ultrasound, and then use non-surgical methods to dissolve the filler or granuloma tissue using intralesional injections. There are many methods using a combination of enzymes, intralesional modulators of scar tissue, and Kenalog to help reduce volume and remaining filler. These techniques require meticulous attention to detail and can be performed at intervals of two to three weeks to achieve longterm effect.

Best,
Dr. Karamanoukian
Realself100 Surgeon

No, if you want to dissolve a hyaluronic acid filler with hyaluronidase, the enzyme will remove the filler.  Hyaluronic acid fillers are Juvederm Ultra and Ultraplus, Restylane and Perlane, Prevelle and some from overseas that are not FDA approved in the United States.  Radiesse is calcium hydroxyapatite and as there is no hyaluroinic acid in it, the enzyme will not break it down.