How long does it take for Hyaluronidase to work?

Hyaluronidase can begin to work immediately.  If I am helping a patient deal with symptoms that cause discomfort (eg nerve or vascular compression/occlusion with fillers) then I will continue to add Hyaluronidase every 10-30 min until I get symptom relief.  If I am doing this to help even out an unintended injection result, then I tend to be more conservative and have the patient return the next day or two and continue to make adjustments until the desired result is achieved.

Hyaluronidase can actually work within hours.  Most of the impact will seen over the first 48 hours with a small amount of change seen over a period of 2 weeks as your body absorbs the filler.  Best Dr. Anil Shah

Hyaluronidase can effectively reduce unwanted hyaluronic acid facial filler.  The effects can be seen early in the first 48 hours, and with additional time thereafter you can see the final results. Raffy Karamanoukian, MD Los Angeles

In my experience 2 to 3 days. It varies from individual to individual and also depends on the dose. Try to undergo small amounts of injections to see if it works well for you. It can sometimes work too well and absorb all the Hyaluronic Acid. If that is your intent, then go ahead. However, sometimes patients like the results but have a small bulge which needs to be flattened.In that situation it is better to start with small amounts and then titrate it based on the response.
Regards

Much of hyaluronidase will take action within the first 24 hours of injection. Additional absorption can occur over the remaining 2 weeks. Keep in mind swelling, irritation at the injection site and some pain can occur when injection of hyaluronidase. Be sure to consult with an experienced practitioner before having your filler dissolved.

Hyaluronidase starts working immediately, once injected into an area of unwanted hyaluronic acid dermal filler. Initially the treatment area may feel a little swollen for a few hours. Possibly red, slightly tender or warm.
Although it starts working immediately visible results from hyaluronidase treatment take 2-3 days to show. 
The treatment works as hyaluronidase (which is an enzyme) triggers the reaction to break up hyaluronic acid (dermal filler) very quickly. This creates some soft fluid product quick reabsorbed by your body.
Further treatment can be arranged if necessary, this is dependent on the amount of volume needed to be removed. 
Following Hyaluronidase treatment to break down unwanted filler your skin will slowly readjust to it's new contours.

Hyaluronidase will start to work within 48 hours and have an effect lasting 2 weeks - additional treatments of hyaluronidase can be given within 2 weeks of the first treatment for additional dissolution remaining Juvederm or Restylane.

A couple things about hyaluronidase

1. It takes 2-3 days to dissolve the filler

2. It may take an additional 2 weeks for absorption of filler/hyaluronidase to occur

3. It may take a couple more months for the skin and local swelling of tissue to resolve

Most of the effect is seen immediately but then the healing process may take some longer time to get rid of the swelling etc..

The effects of hyaluronidase on hyaluronic acid can be seen almost instantly.  Maximum results are achieved in approximately 2-3 days.  This is a great treatment to remove unwanted filler.

Hyaluronidase works in just a few days to dissolve hyaluronic acid filler.  You might get some redness and swelling after the hyaluronidase injections but overall this is a safe and effective way to removed unwanted filler.