Unfortunately, there are no medications, prescription or over-the-counter, that can reliably increase breast size. The FDA (Food and Drug Administration) closely monitors all medications, and have not approved any drugs for this purpose. While Estrogen (a female hormone) stimulates breast tissue, causing it to enlarge, hormonal fluctuations can affect all areas of the body, not just the breast; since many of these effects are negative, hormonal therapy is not used to enlarge the breasts. Do not trust anyone selling an oral aid to increase your breast size. Schedule a consultation appointment with an experienced, Board Certified plastic surgeon to discuss all of your realistic options for increasing the breast size. If cost is a concern, most surgeons offer a variety of financing plans, as well.