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This all depends on how large and area you are using the creams. For example, Melarase cream has 60 gm and you are supposed to apply 1 gm per day, for 60 days. Best, Dr. KaramanoukianLos Angeles
Well over a year. The tube itself is designed to protect it from light. Keeping it in the fridge ensures longevity. For compounded prescriptions its marked 30-90 days, depending where it is made, but in reality it last much longer. You will know when it is expired when it changes colour. Dr Davin Lim. Brisbane. Australia.