Ketoconazole shampoos (Nizoral, etc) promote hair growthKetocaonzole is an antifungal agent and effective for the treatment of seborrheic dermatitis and "dandruff". But research over the past many years has suggested that they help hair loss as well. I often recommend that individuals with genetic hair loss consider use of anti-inflammatory shampoos. Whether these shampoos benefit other types of hair loss is not clear. If you are not sure what type of hair loss you have, please check with your physician. What were the results of ketoconazole studies for genetic hair loss?A 21 month study compared the use of topical minoxidil to ketoconazole 2 % shampoo. Study participants received the 2 % shampoo or an unmedicated shampoo with or without minoxidil 2 %. Interestingly, hair density and follicle size improvements were similar with both ketoconazole and minoxidil regimens.How do ketoconazole shampoos help hair loss?The means by which topical ketoconazole helps hair density and hair growth is unclear, but may be due to is anti-inflammatory effects against T cells and the yeast of the scalp which create inflammation (Malassezia yeast). Ketoconaozle also inhibits steroidogenesis and decreases DHT levels.Medical ReferencesInui. J Dermatol Sci 2007; 45: 66-8.Pierar Franchimont Dermatology 1998; 196: 474-7