Fordyce spots are sebaceous glands that can occur on the mucosa of the lips and genitalia. They are benign. Treatment with lasers or peels can create a pigmentary complication such as hypopigmentation (lightening) which can be permanent, or hyperpigmentation (darkening).
Cauterization, focal strong chemical peels and lasers such as the CO2 and fraxel lasers may help reduce the fordyce spots and photodynamic therapy, all of which are off-label, may help diminish the appearance of the spots. Again, there is a risk of scarring with any laser treatment and scars could look more obvious than the original Fordyce Spots, and some scars could get painful. Speak to your doctor about all the risks before you have any procedure.
The information provided in Dr. Shelton's answer is for educational purposes only and is not intended to constitute medical advice. The information provided should not be relied upon as a substitute for consultations with a qualified health professional who may be familiar with your individual medical needs.