If I move from Finasteride to Dutasteride, how quickly does Dutasteride stop DHT?

Question

If I move from Finasteride to Dutasteride how quickly does dutasteride stop DHT? First dose? I don't want to get off finasteride and have to wait for dutasteride to kick in and lose ground waiting (if that makes sense). If you could help me understand I would really appreciate it. Thank you

Audrey G. Bauer, MD · Answer

If you take finasteride up until the day you start your dutasteride then there will be no gap in the protection against DHT formation. The half life of finasteride is only 7 hours but it blocks DHT formation for about 4 days so as long as you make a direct transition you will in no way "lose ground" as the dutasteride will be effective as soon as you take it. I hope this helps.

Jeff Donovan, MD, PhD · Answer

No, dutasteride does not suppress DHT right away. It takes about 4 weeks. Dutasteride does not suppress all DHT but suppresses more than finasteride. The overall amount of suppression of DHT depends on the dose chosen and frequency of use, Not all males respond to dutasteride so there may be more to some male individual’s balding than DHT. Side effects should be reviewed with a knowledgeable physician before starting and proper follow up appointments is essential.

If I move from Finasteride to Dutasteride, how quickly does Dutasteride stop DHT?

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If I move from Finasteride to Dutasteride, how quickly does Dutasteride stop DHT?

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