Does Exercising Within 4 Days of Botox Make It Wear off Faster?

There is no data nor rationale  that I am aware of to advise patients against exercising for an extended period after receiving Botox.,  I generally advise my patients to avoid exercising on the day of the injections and to keep their head upright for several hours.  Regarding injections after a round of antibiotics there are two antibiotics that can interact with Botox.  The one most commonly mentioned is a family of antibiotics known as aminoglycosides.  These are administered intravenously or intramuscularly not by mouth.  The other one is clindamycin which can be given by mouth.  Regardless the half life of these antibiotics are relatively short and the recommendation to wait a full 30 days seems to be a bit overly cautious.  Perhaps, their overly cautious recommendation is more related to issues of your general health rather than a direct interaction.  If its only a matter of a minor infection, such as an upper respiratory infection, I think waiting several days is more than adequate.  In cases of a more serioius infection it would seem prudent to wait longer but I'm sure in such cases receiving Botox would not even be on your agenda at that time.

With our patients, we usually recommend a break from
strenuous activities (i.e. exercise) on the same day that the injections
were
performed. Unless your doctor has medical concerns specific to your situation, you should be fine to exercise 24 hours afterwards.