What can help to treat these deep accordion lines? (Photo)

I really cannot explain why you have not had improvement from filler, other than to consider the possibility that there was an incorrect choice of filler to get the job done and/or it was improperly injected to achieve the desired improvement. I have been successfully been treating this fairly common problem for many years using a low viscosity, malleable, cohesive HA filler fanned beneath the lines at the appropriate angles to minimize their folding with smiling. Treatment should not take more than about ten minutes to perform.You would be wise to make sure to consult with an experienced, board certified cosmetic dermatologist filler expert. Best of luck.

Hello; In these types of fine wrinkles, it is necessary to increase for collagen and skin thickness; in the subcutaneous tissue. After the subcutaneous tissue is loosened with a cannula, superficially and deeply, collagen stimulation and skin thickening can be achieved by implementing on diluted Ca Hydroxyapatite (Radiesse) or PLA (Sculptura, Lanluma..).