Hello, Your caution regarding new fillers like Ameela (formerly Nucleadyn) is understandable, especially when considering treatment for sensitive areas like the undereye region. Here are some insights to help you make an informed decision: Safety and Approval: Before trying any new filler, it's important to check if it has been approved by relevant health authorities, such as the FDA in the United States or equivalent bodies in other countries. Approval indicates a certain level of safety and efficacy based on clinical trials. Composition and Mechanism: Understanding what the filler is made of and how it works can provide insight into its safety profile. Typically, fillers like hyaluronic acid are popular because they can be dissolved if necessary. If a filler cannot be dissolved, it's crucial to know its long-term effects and how the body metabolizes it. Clinical Experience: Since Ameela/Nucleadyn is relatively new, there may be limited long-term data available. Consulting with a dermatologist or a board-certified plastic surgeon who has experience with this specific filler can provide valuable information about their outcomes and any observed side effects. Potential Risks: As with any injectable treatment, there are potential risks including allergic reactions, infection, or complications related to injection technique. Discuss these with your provider to understand how they plan to minimize such risks. Alternatives: Consider discussing alternative treatments with your provider that have a longer track record of safety and efficacy for undereye concerns. Options like hyaluronic acid fillers, platelet-rich plasma (PRP), or topical treatments might be worth exploring. Ultimately, a thorough consultation with a qualified and experienced practitioner is essential to assess your specific needs and determine the best and safest treatment plan for you. Best regards,