Can spironolactone cause wrinkles?

Spironolactone is an inexpensive pill that is a potassium sparing diuretic, but it is used frequestly by dermatologists for androgen-driven conditions. It acts as an androgen blocker to improve acne, facial hair and alopecia. It does not cause wrinkles.

Spironolactone is a potassium sparing diuretic with testosterone blocking effects that is commonly used for the treatment of hormonal acne.  It does not cause wrinkles.The only thing I think you could be experiencing may be some dehydration.  As a diuretic it is important to replace fluids, drink water.  Dehydration is not good for the appearance of your skin. 

Spiral tone like any synthetic medication has side effects but wrinkle promotion is not one of them. It used for androgen dependent issues such as resistant acne in adult women and slowing down facial hair growth while undergoing laser treatment.