Botox 2 yrs ago caused bumps & thrush on my tongue and throat & ear canals felt excoriated. Drs say no correlation. Tongue/throat healed after 3 mths zantac BID. joint pain, fatigue, foggy brain went away. 2 years later (3 wks ago), got botox again. In 3 days, painful bumps/thrush on tongue/throat, ear canals excoriated. symptom relief with consistent Zantac BID. joint/bone pain, foggy brain, fatigue requiring daily naps. Since botox, mild thyroid issue advanced to hashimotos with peroxidase result > 600