Does Smoking Limit or Shorten the Effects of Restylane?

I don't think we'll know the answer to this question for sure until it is studied and tested.  Our inclination is that over the the time period (approximately 6 months) that Restylane normally takes to degrade, there would not be an appreciable difference between a smoker and non-smoker.

Hi K,
Smoking is very bad for the skin in many ways, resulting in acceleration of the aging of the skin. In addition, smoke degrades hyaluronic acid.
So you have a two fold problem with smoking; you need more product to fill the damaged skin, and then the product disappears more rapidly.
Good luck with giving up the bad habit.
Dr. P

I have not seen that this filler lasts less long in smokers when injected in cheeks and areas other than the lips. There is less duration typically, of any temporary filler, when it is injected into the upper lip lines of smokers because of the pursing that is done to hold the cigarette in the mouth. This activity of the lip’s muscles increases the body’s clearing effect as there is greater circulation of blood flow related to the muscle motion.