Does Exercise Impact the Longevity of Botox and Other Fillers?

I'm a huge fan of Botox and fillers;however,I wonder about the exercise impact.Most say none.I spoke with someone who works for the manufacturer of the most popular "furrow freezer" who said exercise can impact it's longevity.Also, I burned through an out-of-the-box vial (one cheek) of a 12-18 month advertised filler in about 6 months.Im thin but have gained weight not lost.Why conflicting opinions and experiences?is there a point when a lot of filler is lost at once vs. gradual?

Doctor Answers 12

Exercise is not a known cause for faster resolution of botox or fillers

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Exercise is not a known cause for the disappearance of the effects of Botox or fillers. Although there is no scientific studies whose evidence points to the quicker resolution of these products in those that exercise, one does wonder if the increased metabolic rate in pateints that exercise a great deal stimulate the metabolism of the products injected and make them go away more quickly.  Good studies would be difficult to design for such a purpose but would be very interesting.

Manhattan Dermatologic Surgeon
4.9 out of 5 stars 39 reviews

Excercise and longevity of botox and fillers

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We have found that this is up to the individual.  Some folks will break down the product more rapidly than others.  Sometimes it is a biochemical thing.  Sometimes the patient is very animated with the facial muscles.  Sometimes patients who are hypermetabolic will break the Botox and/or filler down faster.  Part of the confusion is the answer is that all these things can influence the breakdown of the product, but what role each plays in the individual is hard to measure.

Jeffrey J. Roth, MD, FACS
Las Vegas Plastic Surgeon
4.6 out of 5 stars 17 reviews

There is absolutely no evidence of this.

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I practice in Los Angeles.  My patients are gym rats for the most part.  I can assure you that vigorous exercise has no bearing on the longevity of these treatments.

Kenneth D. Steinsapir, MD
Beverly Hills Oculoplastic Surgeon
4.9 out of 5 stars 26 reviews

Botox, fillers and exercise

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Although there are no published reports on the impact of exercise on Botox and fillers, anecdotally, some physicians have noted that persons who are highly, metabolically active (marathon runners, exercise enthusiasts) may break down fillers such as hyaluronic acid (Juvederm and Restylane) and calcium hydroxlapitite (Radiesse) quicker.  However, there are no formal studies evaluating or refuting/supporting this claim.

Kristel D. Polder, MD
Dallas Dermatologic Surgeon

Effect of exercise on fillers and botox

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After injecting both neurotoxins and fillers since they came out, I can say that yes, excessive exercise definitely does have the possibility of decreasing the duration of these products.  Excessive exercise produces free radicals  - all biochemical processes in the body such as digestions also product free radicals.  Free radicals then have the ability to break down tissue in the body, as well as products that are injected.  Anyone who exercises a lot should be taking anti-oxidants such as vitamins A, C, E, alpha lipoic acid, co-enzyme Q10 and melatonin to help quench the free radicals.  Longer lasting fillers such as Sculptra, Radiesse and ArteFill may be best for you.  If you had one vial of Sculptra it may be difficult to notice the improvement unless you have side by side before and after photos.  Better to go with longer lasting fillers, but of course this requires seeing a physician who has vast experience in using them!

Laura E. Skellchock, MD (in memoriam)
Boca Raton Dermatologic Surgeon


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There is no exact science of course, to know how long either product will last. I have seen that some clients need to be treated sooner than others, and sometimes the type of  filler used can affect the length of time the volume lasts. Always discuss with your injector your expectations and concerns and know that neither of these products work the same for each person. 

Joseph Serota, MD
Aurora Plastic Surgeon

Botox and fillers

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Botox and fillers should not be impacted at all on acitivites at the gym.  If you lose weight, it may affect the result of fillers because you may become more deflated.

Steven Wallach, MD
New York Plastic Surgeon
4.2 out of 5 stars 30 reviews

Longevity of Botox and injectable fillers and exercise

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Althought the longevity of Botox and injectable fillers can vary between individuals there is no definitive evidence that vigourous exercise will significantly shorten the effectiveness of these products..

Vincent D. Lepore, MD
San Jose Plastic Surgeon
4.7 out of 5 stars 63 reviews

Botox and Exercise

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As the panel members discussed, it would be highly unlikely that your excercise regimen is directly affecting the duration of your dermal fillers and Botox treatments.  Although we agree that there is a small percentage of patients that metabolize the product much quicker than the  expected duration, we don't believe the link is exercise in and of itself. 

However, we do instruct patients to not engage in exercise for four hours following their treatment.  This recommendation is based on the potential for diffusion of the product placed.

You may want to consider whether or not technique (dosing and placement) is a factor. Trying a dermal filler that is not a hyaluronic acid may also be beneficial.  Your reference to the claimed longevity of the product used is oftentimes a claim by the manufacturer based upon "touch up" treatments to reach this benchmark.  Also, if your injector didn't use the correct amount of product or tried to use too little over too large of an area, your outcomes will most likely be disappointing.

Harold J. Kaplan, MD
Los Angeles Facial Plastic Surgeon
4.4 out of 5 stars 7 reviews

Exercise impact on injectables

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I usually ask my patients not to exercise for at least 24 hours following any sort of toxin or filler treatment. I have seen no correlation between exercise regimen and the longevity of injectables.

Peter L. Kopelson, MD
Beverly Hills Dermatologic Surgeon

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.