Thank you for your question. With regard to PRP combined with Acell, there are no well designed studies to document whether there is increased effectiveness versus PRP injections alone. Intuitively, I believe the Acell will enhance the results. There is quite a bit of variability in response to PRP and there are a large number of PRP kits with varying concentrations. There is some general agreement that PRP concentrations of 4-6 times that in blood are most effective in hair restoration. Be sure to ask what concentration PRP the center you go to is using. Most patients respond to a series of PRP injections spaced two months apart. Another option is to add micronized fat to the PRP which is rich in stem cells. Again, no definitive studies as to the effectiveness. Since big pharma is not involved, it is unlikely there will be large multi-center studies to document efficacy. I hope this was helpful - Dr. Moore.