Having applied a topical antibiotic several days prior to laser hair removal is not a contraindication for the procedure in my office. It is not advised to laser very inflamed tissue so if the area is still not healed from the clindamycin then waiting may be advised. In general, topical clindamycin is for acne and so laser hair removal may be done in the area with attempts to avoid severely inflamed or cystic acne lesions due to tenderness mostly. Check with your dermatologist prior to treating.