What is the Most Common Amount of Saline Mixture to Powder Constitution of Botox?

Question

what is the most common mixture of Saline cc's to Botox powder constitution?

Otto Joseph Placik, MD · Answer

We use 2.5cc of Saline to each vial of Botulinum Toxin as suggested in the package insert for a total of 40 units per 1.0 cc. However according to personal preference, it can be mixed witjh 1-5 cc.

Harold J. Kaplan, MD · Answer

The most common dilution rate is 2.5 cc's of saline solution per 100 units of Botox.  If you are a consumer, we would be more interested in the number of Botox units injected as opposed to the dilution rate.  The number of units injected is the best way to understand how the treatment you are receiving compares with that of other offices.  Good luck.

Kenneth D. Steinsapir, MD · Answer

In the instructions that come with the BOTOX vial, doctors are instructed to dilute the BOTOX with 2 to 4 ml of sterile saline.  As you can see from the other responses, some doctors use more saline and there are other who only use 1 ml of saline.  However the most common dilutions are in the 2 to 4 ml range.  

	This means that when the doctor draws up the Botox solution into a one milliliter syringe, the syringe can literally hold any amount of Botox from 100 units, the entire contents of a Botox vial, or as little as 5 units of Botox in the case of one Newport Beach dermatologist who dilutes a vial with 20 ml of saline.  However the typical office is in the 25 unit to 50 unit per 1 ml syringe range.  Occasional an office uses sterile injectable water for their Botox.  It is extremely painful when water instead of saline is used so you are unlikely to go back to an office that makes this mistake.

Christopher V. Pelletiere, MD · Answer

The most standard dilution used for Botox is 5cc per 100 units, or 2u per 0.1cc.  This is what the manufacturer recommends in its packaging, but it can me reconstituted from as little as 1cc to 10cc.

Steven Wallach, MD · Answer

I think there is no specific standard. It is all about comfort. I personaly dilute about 2 cc's to keep it well concentrated so that it is about 50 units/cc. Some dilute it more to be a total of 4 cc's so that it is 25 units/cc.

What is the Most Common Amount of Saline Mixture to Powder Constitution of Botox?

Answers (10)

Answer: Botox Reconstitution

Answer: Botox Reconstitution

Answer: Botox dilution

Answer: Botox dilution

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Everything you need to know about Botox

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What is the Most Common Amount of Saline Mixture to Powder Constitution of Botox?

Answers (10)

Answer: Botox Reconstitution

Answer: Botox Reconstitution

Answer: Botox dilution

Answer: Botox dilution

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Recommended reading

Everything you need to know about Botox

Our mission is to create a world where every investment in modern beauty is Worth It.