Medical literature often suggests that large volume liposuction involves collecting 4-5 liters or more of fluids (these include the fat, anesthetic solution, and blood). Beyond this amount there is a perceived increased risk of complications due to significant fluid shift and blood loss. Of course, the patient's weight should also be taken into account. For instance, the perceived maximum safe limit might be lower in thin patients compared to full-bodied ones. Due to the perceived challenges of large volume liposuction, doctors may elect to stage the surgery, require their patients to have an overnight hospital stay, or perform blood transfusion. But regardless of the liposuctioned amount, the surgery should only be done by a board-certified plastic surgeon who is always required to perform all his operations in an accredited surgical facility or hospital. Also, a team of qualified medical staff, which should include a licensed anaesthesiologist, should always accompany the surgeon to further minimize the risk. Good luck and best wishes.