Lipedema is typically irreversible and does not respond to weight loss. However, avoiding obesity tends to be partially protective. Treatment options are liposuction and possible direct excision of skin and fat or a combination of both. Any type of liposuction can be used, though I would personally avoid the use of VASER or any form of laser liposuction in this particular condition. Liposuction can easily be done avoiding general anesthesia.If this is a procedure you are interested in, then I suggest you consult with an experienced, board-certified plastic surgeon. At times, it is helpful to get more than one opinion, especially in cases that are somewhat unusual or if the person does not have a great experience with lipedema. Best of luck,Mats Hagstrom, M.D.