Can you develop an allergy to Botox even if you never had one before?

Question

My usual skin professional retired. I tried a new person to do Botox (a qualified RN). It hurt way more than usual & sounded funny at one point of injecting. Was very warm and sore for a few hours afterwards. I took some advil to try and get the swelling to go down, did not help. The lady who did the injections told me to take Reactin. Not sure why this would happen as I have had botox before and never had this reaction. Can I have developed an intolerance to Botox or was it something else?

Thomas Buonassisi, MD · Answer

Sorry that happened to you. I have not seen Allergic reactions to Botox itself but it is a remote possibility. It may be the fluid used to dilute it or even related to the depth the needle was inserted. I think it would be helpful for all involved to return to the clinic where you had your treatment and have the overseeing Doctor examine you. They need to get this feedback to improve their service and you need to be re assured.Good luck!

Jonathan Kulbersh, MD · Answer

Unfortunately, it sounds like you were treated by someone who has no expertise in injecting Botox. Your description is not of an allergic reaction, it’s of damage caused by too heavy a hand and possibly an incorrect dilution of the product. Ice and arnica may stop the swelling. Please find a professional to help you next time.  I hope this helps.

Mitchel Goldman, MD · Answer

I think you already answered your question, just by asking it. The injection process felt — and sounded — different to you. Between your description and your photos, this looks like an operator error, NOT A REACTION. Take some time before your next touch-up to find  a board-certified dermatologist who is an expert with Botox, Xeomin and Dysport to treat you. You should not have any of the symptoms you described.

Harold J. Kaplan, MD · Answer

Hi WR. Although allergies to neurotoxins (Botox, Dysport, Xeomin) are rare, they do happen.  When they happen, they look very similar to the reaction you show on your forehead.  Before you jump to that conclusion though, it's probably best to seek out another injector.  You may also want to check with your current injector to review the lot number of the Botox with her and report that to Allergan.  It's possible there was also a problem with the vial.  Good luck.

Jason Emer, MD · Answer

It is unlikely to develop an allergy to Botox after having it successfully before. I recommend following up with your injector. See an expert. Best, Dr. Emer

Can you develop an allergy to Botox even if you never had one before?

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Can you develop an allergy to Botox even if you never had one before?

Answers (9)

Answer: Allergy to Botox?

Answer: Allergy to Botox?

Answer: Developing a Botox/Xeomin/Dysport allergy

Answer: Developing a Botox/Xeomin/Dysport allergy

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Everything you need to know about Botox

Our mission is to create a world where every investment in modern beauty is Worth It.