In the interest of saving time and for overall promoting more gratifying rejuvenation results or of prolonging their duration, it has become common practice to combine in one treatment session the use of neuromodulators (such as Botox, Dysport, and Xeomin) with other rejuvenation techniques, including microdermabrasion or chemical peels, subcision and fractional medical microneedle therapy, and most notably the use of injectable fillers and volumizers, to name just a few. As a rule, when performing both procedures in the same session, it is best to save the Botox for last. The reason for this that, at least theoretically, whatever skin manipulation is required may disperse the injected Botox leading to unwanted side effects, say for example, as in this instance, possible lid droop from the Botox injected into the forehead. In practical terms, after over twenty-three years of experience using Botox for aesthetic reasons, I cannot recall a single instance of this actually happening. So, I think that there is little reason for concern here.As a sidebar, however, I question the value of microdermabrasion, which is in reality little more than "epidermabrasion," the kind of superficial abrasion and removal of the skin cells that might be gotten from a vigorous rubbing with a wash cloth, Buf-Puf or Loofah. I don't know what the problem is in the instance, but it might be worth a consultation with a board certified dermatologist to determine the exact nature of the problem and get a professional recommendation for the best and most cost-effective method to truly address it--be it chemical peels or home prescription medications, etc.