Dear rb9909, Thank you for your clinical post. This is not an often asked question, but DHT stands for Dihydrotestosterone. It is a normal product produced by the human scalp cells, however, it is an intermediary between testosterone in more usable forms of testosterone locally in the hair bulb. Individuals with male pattern hair loss have insufficient amounts of 5-alpha reductase, which is an enzyme necessary to break down DHT into more usable components. As DHT builds up above levels normally seen in the human male scalp it has an effect on the hair bulb cells that produce a hair shaft and affecting the efficiency of the function of the mitrochondria and these cells eventually wither and often parish. As these cells wither, the hair becomes finer and thinner until eventually it’s not produced at all. The use of Finasteride or Propecia blocks production of testosterone, which reduces the amount of DHT levels by producing the amount of the primary product that gets converted into DHT. Thus, DHT is an example of a normal human by-product that is usually broken down further into usable amounts, but in super normal amounts can adversely affect local cells such as the hair bulb. I hope this answers your question. Best of luck. For more information, please review the link below. R. Stephen Mulholland, M.D. Certified Plastic Surgeon Yorkville, Toronto