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Posted under Botox q&a

Could Botox, Acetylcholine, and Memory Problems Be Related?

Sinece Botox works by blocking the transmission of acetylcholine could this cause one to not think clearly? Researched the link between acetylcholine and memory and found that it appears to be important for memory function, specifically short term memory making. Here is an excerpt from the article: Memory starts as a biochemical response in the brain following sensory input. The first change comes at the level of the synapse--junctions between nerve cells. Acetylcholine, a well known neurotransmitter, plays a critical synaptic role in the initial formation of memory. We can think of short-term memory as resulting from a transient change in neurostransmitter levels at synapses. Treatments for memory-deficit problems, like Alzheimer's, in humans often involve enhancing the retention of acetylcholine in brain synapses. Aricept (donepezil hydrochloride), a drug marketed to prevent memory problems, acts by inhibiting the action of the enzyme in the brain that breaks down acetylcholine (acetylcholinesterase). People with moderate levels of dementia can show marked improvement with this sort of treatment. Is there any evidence to support that Botox could not be causing memory issues?

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Dr. Ron Shelton, MD
Answered on Feb 10, 2016
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Dr. James M. Ridgway, MD, FACS
Answered on Apr 25, 2015
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Dr. F. Victor Rueckl, MD (in memoriam)
Answered on Jul 20, 2012
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