Will Xeomin Help with Excessive Sweating (Hyperhidrosis) the Same Way Botox Does?

 heard these products are nearly the same, if Xeomin will help with sweating also, or if that is only something Botox can do?

Doctor Answers 15

All three botulinum toxin products can be used to treat hyperhidrosis.

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Excessive sweating is estimated to affect 2-3% of the population.  Clinicians have now successful used BOTOX, Xeomin, and Dysport to treated hyperhidrosis.  So the answer is yes Xeomin will help with hyperhidrosis

Beverly Hills Oculoplastic Surgeon
4.9 out of 5 stars 26 reviews

Will Xeomin help excessive sweating

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Xeomin and Botox have the same active ingredient, botulinum toxin A

So Xeomin should work as well as Botox for hyperhidrosis.

Xeomin - Can Treat Hyperhidrosis, But Not FDA Approved

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Currently only Botox has FDA approval for the treatment of hyperhidrosis. Xeomin can certainly help prevent excessive sweating, but it is considered off-label when used in this manner, as it does not yet have FDA clearance for this condition. Xeomin is essentially identical to Botox with regard to its active neurotoxin ingredient (botulinum toxin A), except that it does not contain the carrier proteins present with Botox. In theory this will lead to fewer allergic reactions, although the probability of an allergic reaction with Botox is already extremely low.

The hyperhidrosis treatment results for Xeomin and Botox should be similar and last anywhere from 3 months to a year, but will vary on an individual patient basis. Please ensure that you discuss with your healthcare provider further before using Xeomin for hyperhidrosis, as it is still not approved (as of this writing) by the FDA for this condition, although it can treat it successfully.

Stanley Kovak, MD
Oak Brook Physician
4.3 out of 5 stars 7 reviews


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Xeomin can help with hyperhydrosis in the same way that botox does. I would find a reputable provider for injection.

Yes Xeomin Will Work on Hyperhidrosis

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Only Botox is currently FDA approved for the treatment of focal hyperhidrosis.  The axilla (armpits) are one of the most common areas to treat for excessive sweating.  This labeling becomes important only for collecting insurance reimbursement, as many patients can get covered for this procedure if the hyperhidrosis is severe enough.

All three, Botox, Xeomin, and Dysport will work, but Xeomin and Dysport are not FDA labeled for this use.  So in my opinion, it would be a waste of time to try to bill any insurance company for a treatment with Xeomin or Dysport; whereas Botox will often be a covered procedure.

If the patient doesn't have insurance for this problem, and they are self paying, they most certainly should be able to use either Xeomin or Dysport and be charged less than if it were Botox.  They would just need to find a Board Certified Dermatologist who does enough of these kind of treatments to be able to do that.

Marla M. Klein, MD
Lake Oswego Dermatologic Surgeon
5.0 out of 5 stars 9 reviews

Xeomin for hyperhidrosis

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Xeomin is an FDA approved botulinum toxin similar to Botox. Its dilutions are the same as Botox and it lasts as long as Botox, but is much less expensive.  At GoldinSkin, we have replaced Botox for Xeomin for cosmetic injections. The results have been the same.

However, we have not gotten the same results for hyperhidrosis (sweating) as we do with Botox. I do not know the reason.

Harry Goldin, MD
Skokie Dermatologist

Xeomin for Sweating

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Xeomin has been tested and proven to prevent hyperhidrosis under the arms and is FDA-approved for that use. Xeomin works by preventing the release of a chemical, which signals activation of the sweat glands. Results generally last around three months, but depending on the person can last for up to a year. 

Melda A. Isaac, MD
Washington DC Dermatologic Surgeon
5.0 out of 5 stars 6 reviews

Xeomin for Excessive Sweating will Work

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Xeomin will work for excessive sweating, as does Dysport and we know that Botox does. The thing one must know is that only Botox has an FDA approval to treat underarm sweating in the USA. The others can be used, but will be considered an off-label use of the products. This is fine to do, but just know it is an off-label indication.

Michael Gold, MD
Nashville Dermatologic Surgeon
3.9 out of 5 stars 17 reviews

Will Xeomin Help with Excessive Sweating (Hyperhidrosis) the Same Way Botox Does?

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Yes, Xeomin® and Botox®/Botox Cosmetic® both contain the same active ingredient, botulinum toxin A, and so both will prevent/treat hyperhidrosis. 

Manjula Jegasothy, MD
Miami Dermatologist

Will Xeomin Help with Excessive Sweating (Hyperhidrosis) the Same Way Botox Does?

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Yes.  The three neuromodulators on the market (Botox, Xeomin and Dysport) are largely similar and interchangeable in terms of effectiveness and duration of the correction, assuming equivalent dosages (50 units of Botox = 50 units of Xeomin = about 150 units of Dysport).  That applies for all areas of the body, including those treated for hyperhidrosis (usually the axillas = underarms).

I hope that this helps and good luck,

Dr. E

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.