Botox Harmful to Liver and Kidneys?

Isn't it harmful if the Botox is filtered through the liver or kidneys?

Doctor Answers 13

Botox not harmful to liver or kidneys

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}

Botox is placed into the muscle that one wants to effect.  It is designed not to travel systemically.  The quantity of Botox even if it does get into the blood stream is very small.  As of this writing, the drug has been used millions of times without reports of kidney or liver damage.

Las Vegas Plastic Surgeon
4.6 out of 5 stars 17 reviews

Botox safety

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}

You bring up a valid question, but the answer is no.  Used in the correct manner, Botox should not be harmful to your liver and kidneys.  The FDA has approved the use of Botox and with this approval you can be rest assured that it is safe. 

Botox is not toxic to liver/kidneys

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}

Botox is among the most studied and used products on the market. Decades of use now, both "on-label" and "off-label" for medical and cosmetic uses have proven its effectiveness and safety.

Mary P. Lupo, MD
New Orleans Dermatologist
5.0 out of 5 stars 18 reviews

You might also like...

The recommended doses of Botox for cosmetic reasons are proven very safe

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}

There has been a significant number of research performed on the safety and applications of Botox. Botox has been proven to be extremely safe specially when used within FDA Guide lines. The therapeutic applications of Botox continues to grow as it has become the wonder drug. There are by far more medical therapeutic applications for Botox than cosmetic.

Amir Moradi, MD
San Diego Facial Plastic Surgeon
4.0 out of 5 stars 8 reviews

BOTOX Cosmetic is extremely safe-no distant side effects

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}

BOTOX-injected in the usual amounts and locations for cosmetic applications is extremely safe. There have been literally millions of injections of BOTOX for cosmetic reasons and no reports of liver or kidney damage. BOTOX used for cosmetic applications has a local effect on the muscle. Any medication used inappropriately can be harmful. Even aspirin or Tylenol if used in excessive amounts can have adverse effects.

John E. Gross, MD
Los Angeles Plastic Surgeon

Botox does no harm to liver or kidneys

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}

In the recommended amounts and limits to amounts that can be injected in one treatment session, Botox has not been shown to be harmful to the liver or kidneys.

Botox not harmful to the kidneys or liver.

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}

As the others have indicated, Botox generally has no negative effects on the liver or kidneys. Doses should not exceed 500-600 units at any one time. If administered in excessively high doses, Botox can cause botulism, involving muscle paralysis, even death (with approximately 3,000 units).

Bryan K. Chen, MD
San Diego Dermatologist

Botox Not Harmful to Liver and Kidneys

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}

Botox does not cause any damage to liver or kidneys or any other body organs. It has been used since 1980 in thousands of patients without any reports of organ damage.


Tanveer Janjua, MD
Bedminster Facial Plastic Surgeon
5.0 out of 5 stars 126 reviews

BOTOX has proven to be an extremely safe drug

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}

Dear Nanfrnd

Cosmetic BOTOX and Dysport have proven to be extremely safe products with amazing track records of reliability. Like any drug, too much of the product in the wrong place can lead to temporary concerns, but they are temporary and wear off.

Concerns regarding the liver and kidney have never been an issue. BOTOX has not been study for pregnant woman or breast feeding mothers.

Individuals with rare neurological conditions, and those taking certain types of antibiotics are not recommended to receive BOTOX. However, your injecting physician will screen you for these concerns.

These are very safe products when used in the recommended fashion.

Kenneth D. Steinsapir, MD
Beverly Hills Oculoplastic Surgeon
4.9 out of 5 stars 26 reviews

Botox Cosmetic is not known to cause liver or kidney damage

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}

There are no known harmful affects to the liver or kidney with Botox Cosmetic treatments. Injections at recommended doses are not detectable in the blood stream, as there is minimal to no systemic absorption.

Botox Cosmetic affects muscles of the face where it's injected. The usual doses of this treatment do not travel much beyond the area it is treated. Sometimes areas near the injection site are also affected unintentionally. For example, the upper eyelids may become weak or droopy after Botox injections around the eyes or forehead.

Houtan Chaboki, MD
Washington DC Facial Plastic Surgeon
4.9 out of 5 stars 89 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.