Occasionally, Botox takes longer than 10 days to work. I know this from personal experience. Coming back from vacation last summer, I found some Botox that was three weeks old. Not wanting to inject this into a patient (not that there was danger, just a fear of low potency), I had a friend inject it into me ( a dermatologist friend, not my squash playing friend). After ten days it had done nothing. It took a fortnight, but one morning I looked in the mirror and my wrinkles had vanished. If after 14 days, you might wait another two weeks, return and be re-injected. Personally, I would use somewhat lower doses. You can go back again if those doses do not do the job. There are a number explanations why the Botox did not work for you. Perhaps, the vial did not have adequate potency. I had this happen once once, when three of my "regulars" all averred their Botox effect was minimal. This is quite unusual, but it does happen. Maybe the injections were not placed properly, say not deep enough. Maybe the Botox was diluted by someone less experienced. ( Interestingly, today was the first day ever a patient asked me who did the dilutions in my office....I do). Hate to mention this: but maybe the Botox came from a non-Allergan source. Botox must arrive cold, with dry ice. Perhaps, the Botox sat on a dock to long and thawed out, or thawed out and was re-frozen. Maybe you have developed antibodies to Botox or even had antibodies when you started. There is a subset of people, small though it may be, who do not have a result from Botox. These are all possible explanations. It would be best to call up your physician now and tell them of your problem. Do not return in four months with this complaint. If you did so, skepticism, rightfully, would abound.