Botox and Z-pak Safe?

Charles Crutchfield, MD, answered this as I would have. You don't need to call your physician unless your fever and other symptoms don't improve.

There have been no reports that seem to indicate that Botox and Zpak are to be avoided.  General malaise and temperature elevation could be a coincidental viral or bacterial illness unrelated to the Botox or possibly side effects that are rare and temporary in some patients after Botox. Patients that feel such symptoms should see their doctor for followup if the symptoms continue.

The information provided in Dr. Shelton's answer is for educational purposes only and is not intended to constitute medical advice.  The information provided should not be relied upon as a substitute for consultations with a qualified health professional who may be familiar with your individual medical needs.

It is safe to take a Z-pack after having Botox injected.  There have been reports of patients getting mild flu-like symptoms after Botox, but that is very rare.  It is more likely that you have become sick that is independent of your Botox injections.