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Hyaluronidase in nasolabial fold caused dry eye?

Passionate694992Aug 14, 2023
I had migrated filler of my nasolabial fold on the left side dissolved with hyaluronidase. Ever since the procedure, the eye on that side feels unusual and dry and it's very uncomfortable to wear contacts. There is no inflammation, no discharge, no other symptoms, just this strange sensation. I am concerned that the hyaluronidase traveled up the arteries into my orbit and dissolved my natural hyaluronic acid to cause these symptoms. Is there published evidence to suggest it will return?

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Dr. Jason Emer, MD
Dermatologic Surgeon, Board Certified in Dermatology
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Answered on Aug 23, 2023
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Jason Emer, MD

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David M. Kowalczyk, MD, MBA, FACS

Hello! Sorry that you've experienced this. 7 vials is a lot of hyaluronidase to use to dissolve a half syringe of filler. I often use volumes like that for vascular occlusion. There is a risk of the product dissolving surrounding hyaluronic acid - not just the filler - leaving the patient with...

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Sheryl D. Clark, MD, FAAD

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