Does Bella Injectable Filler work permanently?

Doctor Answers 19


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Bellafill is a semi-permanent dermal filler used for acne scars. The collagen provides immediate volume below pitted scars or nasolabial folds to lift them to the level of the surrounding skin. Results are immediate and long lasting. May last up to 5 years.

Fullerton Dermatologic Surgeon

Bellafill is permanent

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Bellafill is composed of 80% bovine (cow) collagen and 20% PMMA microspheres. The PMMA component of the product is permanent. The bovine collagen gets reabsorbed by the body over the 2 months after injection and gets replaced with your own collagen. Hence, the mature implant consists of PMMA microspheres surrounded by macrophages (type of white blood cell), multi-nucleated giant cells (type of macrophage) and collagen. The multi-nucleated giant cells lock the PMMA microspheres in place and prevent their migration. Because Bellafill is a permanent filler it should only be injected by clinicians who have extensive experience and skill injecting fillers. Hope that this information helps!  

PMMA Permanency

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Bellafill is now my filler of choice in the facial rejuvenation patient.  This filler is, in  my opinion, a the first permanent filler available and here's why. 

Plastic surgeons and head and neck surgeons use this same molecule in a sheet form to reconstruct membranes of the neck.  That was told to me personally by a plastic surgeon who is a personal patient of mine.  Now, why would they use a temporary molecule to replace such an important structure in the neck?   They wouldn't. 

It really is the time for patients to begin to seek out a  more permanent correction. 

Will Richardson, MD
Fort Lauderdale Dermatologic Surgeon

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Most studies support a 5 year indication for BellaFill.  The filler is composed of collagen and PMMA microspheres.  Many doctors consider BellaFill to be a 'semipermanent' filler because some of the PMMA might not broken down although the collagen certainly would be.  Patients choosing BellaFill should be sure they want like filler in the areas it is injected so it is likely not a best choice for first time filler users.

John L. Burns Jr., MD
Dallas Plastic Surgeon
4.7 out of 5 stars 56 reviews


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Bellafill, like autologous fat transfer which I also use in my practice, is essentially permanent.  That said, it cannot halt future changes in the skin and soft tissue associated with aging.  The product contains bovine collagen, which serves as a carrier for the durable, more-permanent PMMA. After an extended period of time, the patient may need a "touch-up" of product to maintain a great result.

We have enjoyed the long-lasting effects of Bellafill in our practice.  I recommend consulting with an experienced physician to determine which filler or surgical treatment is appropriate for you.

Best of luck! 

Jeffrey B. Wise, MD, FACS
Wayne Facial Plastic Surgeon
4.9 out of 5 stars 170 reviews

Is Bellafill Permanent?

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Bellafill is essentially permanent. It is a particulate filler that is composed
of a very small amount of PMMA or tiny (40 micron) beads that act as a bio-stimulant. They are non-resorbable. The rest of each syringe of Bellafill (90%)
is comprised of collagen. Bovine
collagen is an old style filler that only lasts 3 months. As it is absorbed over the 3 to 6 months
after an injection of Bellafill, the PMMA stimulates your cells to make new
tissue, replacing the collagen.

The formal FDA studies show that Bellafill will last AT
LEAST 5 YEARS and there are informal studies going back to the original formulations
that show t is still there at 15 years!
I have many patients who still have nice volume replacement at 9 years.

Because it lasts so long, you should be aware of the risks
and benefits of these types of fillers.
I have added a video that may help you.

I hope that helps.

Best regards.

Brian Windle, MD
Kirkland Plastic Surgeon
4.9 out of 5 stars 64 reviews

Bellafill complications and correction

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Bellafill is a semi-permanent filler. Our office is a regional referral center for filler complications and we continue to see complications with patients who have undergone volume enhancement with these types of fillers. 

Dr. Karamanoukian 
Los Angeles

Raffy Karamanoukian, MD, FACS
Los Angeles Plastic Surgeon
4.8 out of 5 stars 95 reviews

Long-lasting wrinkle correction with Bellafill

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While the results of Bellafill are not permanent—they do offer the longest lasting non-surgical correction of lines available on the market today. Known as the “5-year filler,” Bellafill adds volume to plump up wrinkles and smooth the nasal labial folds (smile lines) around the mouth. Our mouth area is mobile, and with age, these lines can deepen considerably. Bellafill is an injectable gel that immediately smooths wrinkles. Its longevity is due to microspheres which promote and support your own collagen; acting like a scaffold to maintain a smooth and natural look for many years to come. It is also very effective in treating acne scars.

Jia Zheng, MD
Vancouver Physician
5.0 out of 5 stars 8 reviews

Bellafill is permanent

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Bellafill is theoretically permanent.  I say theorectically because it has been avaialbe in the US for about 10 years.  The FDA approves the product for 5 years and long term studies are currently underway to show the filler will be long lasting. 

Mike Majmundar, MD
Atlanta Facial Plastic Surgeon
4.5 out of 5 stars 50 reviews

Permanent Fillers Would Be a Problem

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I believe you’re referencing the filler “bellafill”, though there may be some filler on the Canadian market that I’m unaware of named “Bella.” Bellafill will last at least 5 years, but is not permanent. Permanent fillers create problems in the long term, as your face naturally shifts and changes while the injected material does not. For that reason, I caution my patients against a solution that sounds too good to be true.

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.