There are numerous ways to approach anesthesia during CO2 laser resurfacing. I prefer an approach that involves oral sedation where you are still conscious but relaxed, topical anesthesia, and local nerve blocks. This makes the procedure quite comfortable. Most patients rate the discomfort between 2 to 5 out of 10 on a pain scale, meaning it is not completely without discomfort, but is very bearable. Each practitioner that you encounter will likely have their own way of providing anesthesia. Mine has evolved over many, many cases to what it is today, and provides a very comfortable level of anesthesia. Some patients prefer to skip the oral sedation, and they do very well also, but if you have any anxiety preceding the procedure, it is worth adding on that oral medication.