Using self-tanner on your face while taking Accutane (isotretinoin) requires careful consideration due to the increased sensitivity and dryness of the skin associated with the medication. Here are some important points to consider: Safety of Self-Tanner: Generally, self-tanners are safe to use while on Accutane. They work by temporarily staining the outermost layer of the skin and do not penetrate deeply enough to affect the oil glands or the action of isotretinoin. Skin Sensitivity: Accutane can make your skin more sensitive, dry, and prone to irritation. Therefore, it is crucial to choose a self-tanner that is specifically formulated for sensitive skin. Look for products that are fragrance-free and hypoallergenic to minimize the risk of irritation. Patch Test: Before applying self-tanner to your face, perform a patch test on a small area of your skin to ensure there is no adverse reaction. This is especially important while on Accutane, as your skin may react differently than usual. Moisturization: Keep your skin well-moisturized to help counteract the dryness caused by Accutane. Apply a gentle, hydrating moisturizer before using the self-tanner to ensure even application and to help protect your skin. Consult Your Dermatologist: It's always a good idea to consult with your dermatologist before adding new products to your skincare routine while on Accutane. They can provide personalized advice based on your skin type and treatment plan. Using self-tanner should not jeopardize the effectiveness of Accutane as long as you take precautions to protect your sensitive skin.