How Soon Does Apoptosis Start After CoolScuplting Treatment? Is There Anything That Can Reverse Apoptosis Once It Starts?

Question

How soon after does apoptosis of the fat cells begin after a CoolSculpting (zeltiq) treatment? Once apoptosis of the fat cells begin, is there anything that can reverse the apoptosis?

Ron Shelton, MD · Answer

I have seen numerous references to apoptosis with CoolSculpting and although I am not a biochemistry major, my recollection of apoptosis is programmed cell death and the freezing in coolsculpting causes an immediate death of the adiopocyte (fat cell), or necrosis from acute trauma to the cell. However, not all cells get cooled to the same temperature and some fat cells survive depending on the temperature and the length of time the cell reached a certain temperature.

Michael Law, MD · Answer

CoolSculpting Complete works by freezing the body fat to a point where face cells are damaged and programmed for cell death. Once this damage is done, there is no way to reverse the already damaged cell. This apoptotic process happens through a course of weeks maximizing in 3 months time. Vibrational therapy is a way to speed along the lymphatic process. Top providers of CoolSculpting Complete are able to provide rebates to buy one area and get the second area free with complimentary vibrational plate therapy.

Steven Hacker, MD · Answer

We have been performing Coolsculpting since it was FDA approved three years ago in our office. Patients start to see results typically by 4 weeks and can last up to 4 months. In theory , NSAIDS may impact the amount of inflammation that is seen in response to fat cell apoptosis though unclear ultimately how this affects the quantity of fat loss from the procedure.

Daniel Shapiro, MD · Answer

CoolSculpt was developed by Harvard Scientists and is a clinically proven procedure with thousands of happy patients that involves freezing fat cells without damage to your skin. A Vacuum pressure is used to pull targeted areas between cooling plates that over a period of an hour cause fat cells to begin a process called cryolipolysis. This breakdown of the fat cells is complete over a period of 2 to 4 months,

How Soon Does Apoptosis Start After CoolScuplting Treatment? Is There Anything That Can Reverse Apoptosis Once It Starts?

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