Allergic to Sulfa Drugs. Are Restylane and Juvederm Safe?

There are remarkably few allergic reactions to the HA fillers.  This have been one of the important aspects of these products.  Yes the are rare allergic reactions to these products but much less frequent than what was seen with the Collagen fillers.  Specifically, there is no evidence that those who have a sulfa allergies are at increase risk of also having an allergic reaction to the HA fillers.

If someone is allergic to Sulfa they do not have to avoid having Restylane or Sulfa allergies.  These molecules do not cross react.

Both Juvederm and Restylane are antigen-free synthetically derived hyaluronic acid based fillers.  Hyaluronic acid (HA) is substance found abundantly in the human body, making up both intracellular and extracellular matrix.  Therefore, allergy to HA is virtually impossible.  Neither filler has any sulfa component in it.