PRP Facial Rejuvenation Fact Review?

Does PRP facial rejuvenation work? How would you compare it to Botox and fillers?

Doctor Answers 8

PRP is excellent for Facial Rejuvenation

PRP, or Autologous Platelet Healing Gel is made from a natural component of the patient’s own blood that is used to aid in the quicker recovery following certain cosmetic procedures. 

I have been using platelet healing gel since 2000 and, each year, use platelet healing gel in over 500 patients. This process is truly changing the way many plastic surgical procedures are performed. It is used at the end of a procedure and sprayed under the skin where it reduces bruising, swelling and speeds healing. Because it is so concentrated, it acts as a wound sealant (tissue glue). This eliminates the need for dressings and drains, and also reduces the incidence of hematomas (blood collections) and seromas (fluid collections). It also reduces bruising and swelling. In addition, it promotes more rapid healing by secreting healing and growth factors which enhance recovery.

More recently, doctors are using PRP in combination with fillers or lasers to enhance results. Stem-cell technology uniquely blended with Hyaluronic acid therapy (Juvederm, Restylane & Belotero) and the most advanced non-ablative fractional laser skin resurfacing help to create a natural result.   These harnessed stem cells facilitate healing and add volume to help tighten skin.



Melbourne Facial Plastic Surgeon
4.7 out of 5 stars 116 reviews

PRP Platelet Rich Plasma

Hi Tony

I so love questions from the community because it keeps me aware of all the crazy things out there.

Consider finding my Realself article on eyetight that talks about how to personally evaluate new technology.

PRP claims improvement in facial appearance with the injection of the patient's own plasma. Essentially, blood is drawn from you, spun and the plasma in injected under the skin with the implication that growth factors in this liquid stimulate rejuvenation. The problem with this great idea is there is no a shred of scientific evidence that it even remotely works. The before and after pictures of this procedure on various web sites are either very unimpressive, show patients who have clearly had other services, or have obvious manipulation of the lighting between the before and after images. If you want proven treatment stick with BOTOX and Restylane. If you want something that is unproven and most likely ineffective, try RPR.

Kenneth D. Steinsapir, MD
Beverly Hills Oculoplastic Surgeon
4.9 out of 5 stars 26 reviews


PRP can be layered onto the skin and microneedling technique will drive it into the skin. It results in dermal thickening and improvement.  PRP works at the skin level, Botox is for muscular movement and tension under the skin, and fillers are layered under the skin for lifting wrinkles or facial deflation.

Keith Denkler, MD
Marin Plastic Surgeon
5.0 out of 5 stars 18 reviews

Does PRP work for facial rejuvenation?

Hi Tony-

Thank you for your question. In my opinion, PRP which stands for Platelets Rich Plasma is very different from Botox and fillers. PRP improves the skin texture and give the skin a glow by improving skin quality. It is best when combined with micro needling. PRP is being also used for hair rejuvenation, acne scars, wrinkles, tear trough correction etc... Botox corrects wrinkles by relaxing the underlying muscle. Fillers correct volume loss and wrinkles by adding volume. 

I hope this helps. Best wishes. 

Bernard S. Salameh, MD
Bowling Green Physician
5.0 out of 5 stars 17 reviews

Vampire Facial vs Fillers

Natural way of rejuvenating the skin. It is not a face lift – it is more about rejuvenating skin.  It does not add volume – so if that is your goal Dr. Ebrahim recommends that you think about dermal fillers.

The Vampire Facial will enhance skin texture and tone with results lasting up to 18 months.

Shehla Ebrahim, MD
Vancouver Physician
4.9 out of 5 stars 9 reviews


PRP takes growth factors from you platelets in your blood and taps the growth factors into the superficial layers of your skin with minimal discomfort. The growth factors stimulate your skin’s collagen to repair the damage done to your skin over the ages. We often combine PRP with Redensity I to significantly improve the skin’s brightness and luminosity. One session of each are required monthly and one session is repeated every 6 months. In comparison, Botox works in the muscle underlying the skin to relax the muscle whereas fillers are used to build up loss of tissue under the skin.

David A. F. Ellis, MD
Toronto Facial Plastic Surgeon
3.5 out of 5 stars 8 reviews

PRP works especially with the Radiant Facial

Yes PRP works but it's different from fillers and botox in that it's a stimulator of tissue.  Botox slows or completely paralyzes muscle so that it doesn't move and therefore doesn't result in wrinkling of the skin.  Fillers provide immediate volume restoration by filling in wrinkles, folds, and depressions.  PRP stimulates new tissue and boosts existing tissue.  PRP can be injected into wrinkles, folds, and depressions but it can also be delivered into the skin to give an improved glow as seen in our Radiant Facial.   

Justin Yovino, MD, FACS
Beverly Hills Plastic Surgeon
4.9 out of 5 stars 91 reviews

PRP for rejuvenation

This is a modality that is not widely accepted. Some things in medicine may make common sense and not necessarily medical sense. For example: A raisin is a dehydrated grape but that does not mean rubbing water on a raisin will turn it into a grape. PRP is a concentrated portion of your blood. However when you bleed under the skin (bruises or hematomas) the area does not look younger.

Otto Joseph Placik, MD
Chicago Plastic Surgeon
4.9 out of 5 stars 81 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.