Can Duac and Botox Be Used at the Same Time?

I really can not see this being much of a problem.
First, the amount of Clincamycin absorbed through the skin would not be that significant. When topical clindamycin first came out ( Cleocin, Upjohn), we did fear pseudomembranous colitis. Some of us were reluctant to use it on larger areas such as the back. The development of this problem in a patient at the time, stirred up a fair amount of anxiety. However, this problem has not been borne out and while, certainly we might watch for it, in everyday practice this has not been much of a concern.
Any problem with Botox would be even less. It is not contradindicated to use Botox and Oral Clincamycin ( a lincosamide) or aminoglycosides. One might be cautious, since this group of drugs does interfere somewhat with neuromuscular transmission. But the two may be used together if your physician feels it would not be a problem. Caution would be most appropriate if one is using large doses of Botox.
I see no problem at all if using a topical containing Clindamycin in the usual cosmetic dosages of Botox.