As others have mentioned, Botox in the US comes in 100 U and 50 U vials. The 100 U one is the most common. Different providers dilute it in different ways. Personally, I use 2cc of saline. More important than the dilution is the number of units injected in a given area. HOWEVER, if too much fluid is injected in one area, then diffusion is greater and nearby muscles can be affected more than if a smaller amount of fluid is used. Therefore, in my experience, if 4 cc of saline is used for dilution and the frown lines between the brows are treated, there is a higher likelihood of botox migrating to the eyelid muscle, which can cause drooping. I hope this helps you.