What caused my allergic reaction to Restylane?

I have (what I consider) deep nasolabial lines. I have tried using Restylane twice (about 9 months apart) to correct them. Each time with a different doctor.
Both times after about 2 -4 weeks on the area right next to my nostrils I developed granulomas. The second time I was injected the granuloma that developed on the right side went up to under my right eye. First the right side of my face was swollen. Then a hard line up to my eye. I was given steroid injections at the injection site and pills to take. It eventually went away.
I was told by the second Dr. that did the injections that what happened to me was so rare she hadn't heard of it or seen it happen before. She was convinced that I am allergic to the protein that binds it.
I have two questions.
1. Has anyone had this happen to them or heard of it happening to someone in the past?
2. I have been looking for another injectable without the protein and from what I have read Radiesse is made of other components. Has anyone heard of similiar allergic reactions to Radiesse?
Please help :-)

2 answers to “What caused my allergic reaction to...”

A: Granuloma formation rare after Restylane or Juvederm filler injection

William Ting, MD

True skin allergic reaction to hyaluronic acid fillers such as Restylane or Juvederm is exceedingly rare. Granuloma formation can seldomly happen after hyaluronic acid injection and often is attributed to less than perfect hygiene skin preparation prior to injection rather than the hyaluronic acid itself.

A: A granuloma is not an allergy

Steven F. Weiner, MD

Granulomas are when the body reacts to a substance and considers it foreign material. The is an intense inflammatory response, but not an allergy. This creates redness and swelling. Steroids are usually given to reduce the swelling. Sometimes, dissolving the filler with hyaluronidase will resolve the... more

Comments

SusanM
1 post
18 Feb 2009

Yes, I had Radiesse approx 12 days ago, I still have bumps all over the injection site, they are sore and very sensitive to the touch. When I try to sleep it is painful which is why I'm posting this at 12:45 AM. My doctor said it's NOT uncommon. I don't know what to do. Can anyone help? Should I go to a doctor?

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