I have experience with Vanquish, CoolSculpting and Zerona. We have had our CoolSculpting device now for over 5 years and were the first office in Orange County to have Vanquish. We obtained our Vanquish in January, 2014. We have had very nice results from both of these devices. CoolSculpting works by freezing the fat cells and causing the cells to die. This device is ideal for localized areas of fat such as the 'love handles' and 'bra rolls'. The downside of CoolSculpting is that it takes one hour per localized area. Vanquish utilizes a large panel which lies very close to the skin and can cover a broad area. Vanquish then heats up the fat cells to over 110 degrees fahrenheit to cause the fat cells to die as well. As you can see, you can reduce fat cells by taking them to either extreme in temperature for enough time. Both devices take some time to see the final results. Results can be impressive in certain patients. I don't compare the results to liposuction as I feel I can obtain better results surgically, but not everyone is interested in surgery. It is best to obtain a consultation to see which device is best for you. With regards to Zerona, it utilizes low level energy to supposedly cause fat cells to 'leak'. I had the device for several results and patients seemed happy; however, I returned the device as I felt they achieved their results from the exercise, diet and supplements that were recommended with it.