Perlane Vs Juvederm

This is a great question and one which will be answered differently by different physicians which should indicate to you that for the most part they are fairly equal. Remember that Juvederm has 2 different types (Ultra and Ultra Plus) They do not last equally in my experience and most will agree that Ultra Plus easily outlasts Ultra. Expect Perlane and Juvederm to last around 12 months. Both seem to stimulate your own natural collagen growth which may be why we see what appears to be even... more

Hi Demason, Perlane and Juviderm are both hyaluronic acid products that last for about 6 to 9 months in most patients’ nasolabial folds. Recent studies have shown that hyaluronic acid stimulates natural collagen production so that even when they wear off there is still improvement over the original fold. Other good fillers for the NLF are Radiesse, Evolence, Elevess, and likely many more to be released in the near future. I would be very careful of "permanent" fillers as... more

Perlane is a more dense dermal filler, it is used for larger volume restoration, or for filling deeper facial folds. Juvederm formulations can be used for more subtle changes, such as defining a cupid’s bow, which Perlane cannot.

That depends on how deep your NLF's are.  For superficial folds, either Juvederm, Restylane or Perlane are all suitable.  Restylane and Juvederm are smaller molecule fillers meant to be placed within the layers of the skin for more superficial folds, lines and around the lips.  Perlane and Juvederm Ultra Plus are larger molecules that must be placed below the skin within the deeper subcutaneous fatty tissues for the correction of deeper folds or to shape the Cheeks, Chin... more

Both Perlane and Juvederm are great choices for treating the nasolabial folds.  They are both hyaluronic acids that last long, are very forgiving, and can be reversed if necessary.  Their use in different areas is largely up to the preference of the practitioner and patient.  However, there are some very important distinctions: Juvederm  is probably better than Perlane for treating the lips as it has a silky almost liquid-like consistency. However, this... more

Perlane is the thicker form of a hyaluronic acid based filler which is compared to the thicker form of Juvederm which is Juvederm Ultra Plus.    Both of these now come with lidocaine local anesthetic already mixed in and are called Perlane-L and Juvederm Ultra Plus XC.   These new forms are much less painful.

If you want to compare Perlane to juvederm ultra plus, I think that they are very similar products and will last about the same amount of time.

Perlane is designed for deeper planes than Restylane or Juvederm but if it is injected too deep, it won't stay around to support the skin. You may need more filler and you can try Juvederm or Restylane done more superficially.

Both Juvederm and Perlane are safe and effective hyaluronic acid fillers for the nasolabial folds. Perlane may be slightly better for deeper lines as it is thicker (has higher G prime), while Juvederm might be nice for softer, less deep lines. Both last 6-12 months in the nasolabial folds; each person breaks the filler down at different rates. If there are problems (uncommon), then both can be simply dissolved with hyaluronidase (an antidote).

Perlane is effective for treatment of deeper nasolabial folds. Juvederm allows for more subtle improvement but is generally more flexible as it also corrects deeper nasolabial folds..