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How Long Does Perlane Last?

I thought Perlane was supposed to last longer than other non-permanent wrinkles fillers, but a lot of the Perlane reviews on this site say that it didn't last very long.  How long is Perlane supposed to last? 

Doctor Answers 20

Perlane results duration

Perlane typically lasts 6-12 months, but it depends where it is injected. If injected onto the cheekbones, I find it lasts around 12 months, while in the nasolabial folds and marionette lines it is 6-9 months since there is more movement in this area. Duration is partly affected by injection technique as well.

Toronto Dermatologic Surgeon
5.0 out of 5 stars 32 reviews

Perlane longevity is similar to Restylane and Juvederm

Perlane is a hyaluronic acid (HA) filler material similar in structure to Restylane and Juvederm. It is processed to be thicker and designed for deeper wrinkles or subcutaneous augmentation.

The duration of the filling effect seems to be similar to the other HA products. Realistically a 6-12 month effect is to be expected, depending on the location injected.

Ira D. Papel, MD
Baltimore Facial Plastic Surgeon
5.0 out of 5 stars 18 reviews

Perlane lasts upto 9 months

Perlane has been lasting from 6 up to 9 months in my practice over the past several years.

Michael A. Persky, MD
Encino Facial Plastic Surgeon
5.0 out of 5 stars 25 reviews

Perlane time-line

I tell my patients that Perlane lasts 9-12 months but it is slowly degrading and that they may want to come in for a touch-up at 6 months.
If they need 2 syringes at the 1st visit, they will only need 1 syringe at 6 months.
That keeps that close to 100% correction all year round!

Sheila S. Nazarian, MD
Beverly Hills Plastic Surgeon
5.0 out of 5 stars 11 reviews


Perlane should typically last 9-12 months, however people metabolize products at different rates so the same may not last longer on one person than another.

Jeffrey W. Hall, MD
Austin Plastic Surgeon
4.5 out of 5 stars 15 reviews

Perlane - How long does it last?

Perlane is FDA approved to last 8-12 months; however, if a touch up of the product is performed at 4 months, you can expect it to last up to 18 months.  It will last longer in the cheeks and shorter around the nasolabial folds and lips.  Good Luck!

Mike Majmundar, MD
Atlanta Facial Plastic Surgeon
5.0 out of 5 stars 34 reviews

How long does Perlane last? 6 months average

In short, most will get 6 months or more correction with Perlane. Results do vary with injection technique, skin thickness, and the amount of movement in the area treated. 

This product works best for moderate lines and wrinkles as well as lip enhancement. 

Robert S. Bader, MD
Miami Dermatologic Surgeon
5.0 out of 5 stars 3 reviews

Perlane and duration of efficacy

Perlane is formulated to last about the same as other hyaluronic acid based fillers. The difference in the products is the molecule size, which is much greater than that of Restylane or Juvederm and is typically used in areas with deeper volume loss.

Sam Naficy, MD
Seattle Facial Plastic Surgeon
5.0 out of 5 stars 166 reviews

Perlane, Juvederm, Fill NLF's, Face Fillers

Perlane lasts about 8 months in my experience.  Radiesse lasts a  bit longer, typically around 12 months.  Both are great fillers and have their pluses and minuses. 

Francis R. Palmer, III, MD
Beverly Hills Facial Plastic Surgeon
4.5 out of 5 stars 12 reviews

Perlane lasts up to 12 months.

Perlane is my filler of choice for midface volume correction.  The product is safe, effective, and feels natural.  I have treated a number of complications with other non-hyalorunic acid fillers in this area.  I tend to favor a slightly shorter duration versus greater risk and no reversibility. 

Benjamin Bassichis, MD, FACS
Dallas Facial Plastic Surgeon
5.0 out of 5 stars 35 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.