How Long Does Perlane Last?

Perlane has been lasting from 6 up to 9 months in my practice over the past several years.

I tell my patients that Perlane lasts 9-12 months but it is slowly degrading and that they may want to come in for a touch-up at 6 months.If they need 2 syringes at the 1st visit, they will only need 1 syringe at 6 months.That keeps that close to 100% correction all year round!

Perlane is FDA approved to last 8-12 months; however, if a touch up of the product is performed at 4 months, you can expect it to last up to 18 months.  It will last longer in the cheeks and shorter around the nasolabial folds and lips.  Good Luck!

Perlane is formulated to last about the same as other hyaluronic acid based fillers. The difference in the products is the molecule size, which is much greater than that of Restylane or Juvederm and is typically used in areas with deeper volume loss.

Perlane is my filler of choice for midface volume correction.  The product is safe, effective, and feels natural.  I have treated a number of complications with other non-hyalorunic acid fillers in this area.  I tend to favor a slightly shorter duration versus greater risk and no reversibility. 

Perlane is made of hyaluronic acid; just like Restylane and Juvederm. It is thicker than Restylane, so it is best for treating the nasolabial folds. The manufacturer recommends anywhere from 4.5 months to 9 months for follow-up treatments. We have also noticed that patients who followed the treatment regimen regularly, they are seeing the results lasting up to 18 months.

Perlane and Restylane are both hyaluronic acid fillers. Restylane results can last up to 18 months from the initial treatment of Nasolabial folds if you receive full correction and a follow-up treatment at 4.5 months or nine months per Medicis. I have noticed that patients get up to 8 months of full correction after initial treatment. and then need a follow up refinement.

Both Perlane and Restylane are hyaluronic acid fillers. Restylane typically lasts 4-9 months and Perlane slightly longer between 6-9 months. Both are reversible by hyaluronidase in the rare event of nodules.

Perlane is marketed as lasting longer than Restylane, from 9 months to a year. In my practice it does last longer, but shows great variability in duration from patient to patient. In my experience, results with all the fillers are better maintained if a full correction is done or if touch up injections are done before all the correction is lost.

Perlane is a hyaluronic acid (HA) filler material similar in structure to Restylane and Juvederm. It is processed to be thicker and designed for deeper wrinkles or subcutaneous augmentation.
The duration of the filling effect seems to be similar to the other HA products. Realistically a 6-12 month effect is to be expected, depending on the location injected.