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Perlane Vs Juvederm Ultra Plus - Best Filler for Nasolabial Folds?

asked 3 years ago by suzel in Loxahatchee, Fl USA
Latest answer by Erez Sternberg, MD
Question viewed 43,621 times
Tags: nasolabial folds, comparison

I have pretty deep nasolabial folds. My injector has offered me my choice of fillers. I would prefer Perlane or Juvederm Ultra Plus, both of which he said would be good choices for me. (I don't really want to try Radiesse quite yet since that one can't be dissolved if I don't like the results). Which of those 2 fillers do most doctors think lasts longer? Does anybody have a good reason for preferring one of those over the other? I can't find any comparisons online. Thanks!

16 answers to Perlane Vs Juvederm Ultra Plus - Best Filler for Nasolabial Folds?

+4

Juvederm Ultra Plus vs. Perlane

Both Juvederm Ultra Plus and Perlane are hyaluronic acid based dermal fillers that are excellent for nasolabial folds. There is no clear leader between the two. The choice is personal preference of both the patient and the injector.
Kris M. Reddy, MD, FACS

West Palm Beach Plastic Surgeon
+3

Perlane and Juvederm Ultra Plus are competitors and are...

Perlane and Juvederm Ultra Plus are competitors and are designed to be an alternative to Retylane and Juvderm Ultra. They are all hyaluronic acid fillers, and so are not permanent, but both Perlane and Juvederm Ultra Plus are a bit thicker (more dense) so they last longer. In my experience, you can expect each to last anywhere from 9 to 12 months. I don't think there is a significant difference in terms of how long they last. What is more important is the technique of injection: if it... more
Shahram Salemy, MD

Seattle Plastic Surgeon
+2

Perlane and Juvederm Ultra Plus are equally good for deeper nasolabial correction.

Suzel, Do not spend too much more time trying to research to find out which is better. The reason you can't find an easy answer is that it probably doesn 't make a predictable difference. As the other doctors have said, the Juvederm family of fillers tend to come with less in each syringe, so you may get more for your dollar with Perlane if the syringes from both companies cost the same to you. The syringes are also different shapes and different physicians have personal... more
Jessica J. Krant, MD, MPH

Manhattan Dermatologic Surgeon
+2

Perlane or Juvederm Ultra Plus

Pepsi or Coke? I have used both and found no clear winner. The Juvederm comes in a 0.7 cc syringe, the Perlane in a 1 cc syringe. Both last a similar length of time. Personally, I would gauge which of them was more cost effective depending on how many syringes were needed to correct the folds.
Peter A. Aldea, MD

Memphis Plastic Surgeon
+2

Perlane vs. Juviderm Ultra Plus

Perlane and Juvederm Ultra Plus are thicker forms of a dermal filler call Hyaluronic acid which are often used for deeper facial lines such as the Nasolabial folds (line from the nose to the lip sometimes called smile line) and marionette lines near the corners of the mouth. Although the competing companies that produce these fillers each claim their product is the best I have found them to be very similar. They usually last about 9 months with the first injection and depending on how... more
David L. Mobley, MD

Sarasota Plastic Surgeon
+1

Which is the best filler to use: Juvaderm Ultra Plus or Perlane?

The short answer is: whichever one you get the best deal on. As you can see from the answers to your question, both are very similar HA (hyaluronic acid) fillers and last about the same amount of time, 6-9 months. So, find a good plastic surgeon and use the one that saves you money. Most offices, like ours, will carry both products.
Erez Sternberg, MD

Jacksonville Plastic Surgeon
+1

Perlane, Juvederm, Fill NLF's, Face Fillers

Perlane or Juvederm Ultra PLus are both great choices for deep NLF's.  We use both but I prefer how Perlane feels in the tissues and how beautifully it molds into place, so I'd vote for Perlane.  I also use lots of Radiesse but unless patients insist on it because it lasts longer, I try to avoid using it in the NLF's.  When patients smile after radiesse in their NLF's, you can sometimes see the line of Radiesse under the skin which doesn't happen when using... more
Francis R. Palmer, III, MD

Beverly Hills Facial Plastic Surgeon
+1

Perlane Vs. Juvederm Ultra Plus

Juvederm Ultra Plus and Perlane are both excellent products for injecting moderate to deep Nasolabial folds. They are nearly the same product made by competing companies. You should make your decision based upon injector preference and price point - depending on the number of syringes needed. You should be aware of the fact that Juvederm comes in a 0.8cc syringe and Perlane comes in an overfilled 1.0cc syringe (nearly 1.2 cc of product). Dr. Grant Stevens more
Grant Stevens, MD

Los Angeles Plastic Surgeon
+1

Juvaderm vs Perlane

I think that juvaderm ultra plus and perlane are about the same.   They both last about 9 months to a year.  I do not have a preference.
Steven Wallach, MD

Manhattan Plastic Surgeon
+1

Perlane vs. Juvederm Ultra Plus for nasolabial fold wrinkles

Both Perlane and Juvederm Ultra Plus are good options for nasolabial fold lines. Both are longer lasting hyaluronic acid-based fillers with comparable texture, longevity, and safety records. You should go with whichever filler that your physician injector is comfortable with a price point that makes sense to you.
William Ting, MD

Bay Area Dermatologic Surgeon
+1

Juvederm Ultra Plus Vs Perlane

Both are excellent products with very similar applications, safety profiles, and duration.  
Anil R. Shah, MD

Chicago Facial Plastic Surgeon
+1

The all important difference between Juvederm and Perlane

Both Juvederm and Perlane are roughly the same and the choice is probably dependant on what the injector prefers and cost for the patient.
Chris Thiagarajah, MD

Washington DC Oculoplastic Surgeon
+1

Perlane versus Juvederm Ultra Pulse

Both products are large particle hyaluronic acid fillers meaning that they are a little more dense and can possibly last longer. In Jacksonville, Juvederm Ultra Plus is commonly used to fill the lips, nasolabial folds, etc and has an excellent track record. To learn more about soft-tissue fillers, please visit our site below.
Ankit Desai, MD

Jacksonville Plastic Surgeon
+1

Perlane vs. Juvederm Ultra Plus for Nasolabial folds

Perlane and Juvederm Ultra Plus are both larger particle hyaluronic acid fillers and are great for improving the Nasolabial folds. They last about the same about of time. It's up you and your injector.
Vincent N. Zubowicz, MD

Atlanta Plastic Surgeon
+1

Juvederm great for nasolabial folds.

Hi. I don't have experience with Perlane.  In Manhattan, Juvederm is more commonly used.  They really are different products.  Juvederm is more "fluid", and I think more likely to give a smooth result.  It may also last longer.
George J. Beraka, MD

Manhattan Plastic Surgeon
+1

Both Perlane and Juvederm Ultra Plus are efficacious for improvement of nasolabial folds

Both of these more concentrated, larger particle Hyaluronic acid fillers are excellent for improving nasolabial folds, however you may require 2-3 syringes for complete effect. The choice is really what your injector prefers. Over the last 3 years, PS have elucidated that the reason for nasolabial folds is persistence of fat adjacent to the nasolabial lines and lipoatrophy of fat lateral to the folds. Occasionally, Sculptra may be used to augment the cheek hollows, which does a great job... more
Lavinia Chong, MD

Orange County Plastic Surgeon

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