Ask a doctor

Is Juvederm Voluma an Alternative to Radiesse?

How does Juvederm Voluma stack up against Radiesse for larger-area volumizing, such as cheek hollows? Or is it so new that not many physicians have tried it yet?

Doctor Answers 48

Juvéderm Voluma® is an excellent alternative to Radiesse®, and can be reversed.

Juvéderm Voluma® is an excellent alternative to Radiesse®, and [unlike Radiesse®] can be easily reversed by injection of hyaluronidase in the rare event of a problem.

Another advantage of Juvéderm Voluma® is that [at least in Canada] it comes with lidocaine anesthetic in it, improving patient comfort. Radiesse®, by contrast, hurts a lot unless the doctor adds lidocaine, and the process of mixing in lidocaine in the office carries the risks of contamination and/or error.

Finally, patients treated with Juvéderm Voluma® often look good compared with their baseline photos 12-18 months after treatment -- about the same duration of cosmetic benefit as Radiesse®.


Niagara Falls Dermatologic Surgeon
4.5 out of 5 stars 3 reviews

Voluma and Radiesse: Excellent for Different Kinds of Correction

In answer to your question, Radiesse actually earned FDA approval well before Juvederm Voluma. I recommend and use both fillers, however, for the correction of different anti-aging issues. While both are long-lasting, Voluma is a hyaluronic acid (HA) filler. More importantly, it is the first and only HA filler to receive FDA approval for deep injection into the cheeks for the purpose of uplifting and restoring youthful volume to the apex, apple, and cheek hollow. Voluma does this beautifully, and in doing so, smoothes facial wrinkles and lifts the sagging skin that causes deep nasolabial folds.
On the other hand, Radiesse is made from Calcium Hydroxylapatite (CAHA) microspheres suspended in a dense gel. It is typically injected into the folds and creases that run from nose to mouth (nasolabial folds) and mouth to chin (marionette lines) for the purpose of smoothing and plumping. However, Radiesse is not approved for deep injection into the cheek area to lift the cheek area and fill in cheek hollows. In short, neither injectable is a replacement or alternative for the other. Both are excellent, but for different types of correction.

Hal Michael Bass, MD
Miami Plastic Surgeon
4.5 out of 5 stars 39 reviews

How does Juvederm Voluma stack up against Radiesse?

Juvederm Voluma XC received FDA approval to be used in the USA October 23, 2013. Voluma is an injectable hyaluronic acid gel like other Juvederm products, Restylane, and Perlane. Voluma is the first and only filler that is FDA-approved to instantly add volume to the cheek area. The filler gives a subtle, natural lift, that helps restore a more youthful look and add volume to the cheek area. The good news is that Juvederm Voluma lasts 2 years! (this is double the time of regular Juvederm Ultra and Ultra Plus). 

In my mind, the main advantage of Radiesse was that it was longer lasting than the previously-available hyaluronic acid products.  Voluma now lasts just as long. In addition, Voluma has the added advantage that if you are unhappy with the results of your treatment, it can be dissolved, whereas Radiesse can not.

Dara Liotta, MD
New York Facial Plastic Surgeon
5.0 out of 5 stars 18 reviews

Juvederm Voluma vs. Radiesse: Why We Like It Better

Even though we have only had Juvederm Voluma XC for a year or so, we can already see that we’ll be using less and less Radiesse in the future. Juvederm Voluma is made of hyaluronic acid while Radiesse is calcium hydroxylapatite (CaHA). Here is why we prefer the Voluma’s thick cross linked hyaluronic acid to Radiesse’s calcium hydroxylapatite formula.
  1. Voluma can be dissolved for safety reasons or if a patient decides he or she does not like it. On the other hand, Radiesse is composed of very tiny smooth calcium hydroxylapatite (CaHA) microspheres which form a scaffold that can’t be dissolved. Once injected, the body’s own collagen grows around the scaffold.
  2. Voluma lasts longer. Clinical studies are showing that Juvederm Voluma lasts about two years as opposed to the 12-18 months of Radiesse.
  3. Voluma’s thick gel formulation is softer and more natural-feeling than the toothpaste consistency of Radiesse. It injects easier with much less bruising and swelling. Frankly we are surprised at how little bruising and swelling we are seeing with Voluma when the patient has followed our easy instructions on how to prevent bruising. The link to that is below. Using the flexible cannula sure does help!
Although Voluma and Radiesse cost the same ($900 per syringe), Allergan has the Brilliant Distinctions program which is a big cost-savings, especially when combined with the increased longevity of Voluma.
Both Radiesse and Voluma should never be used in the lips or under the eyes.

David B. Reath, MD
Knoxville Plastic Surgeon
5.0 out of 5 stars 94 reviews

Voluma, Radiesse and the filler toolbox

The ever increasing number of fillers on the market is a beautiful thing in
experienced hands, as it just further expands the number of tools in our toolbox.

When your physician has knowledge of this subtle differences between these fillers, those different properties can be exploited to get the most precise and specific results for your personal needs.

Voluma and Radiesse do have overlapping uses, yes, but they are entirely different molecules with very different properties. Voluma was the first filler approved or the cheek area by the FDA, but Radiesse has been used there for several years prior with excellent results and duration of correction.

Voluma is unique on the market now since it is the hyaluronic acid filler that has the longest duration. I have personally seen people from the initial trials who were still having correction as far as four years out. Being a hyaluronic acid it also comes with the advantage of being easily reversible/dissolvable.

Radiesse is a completely unique molecule on the market, and is not dissolvable, but tends to be less expensive.

Make sure you find someone with great experience utilizing all the different products on the market. This is something that's definitely easier said than done.

To guarantee you're receiving the highest level of care, seek out a dermatologic surgeon, oculoplastic surgeon, facial plastic surgeon or plastic surgeon who is board certified and fellowship trained in one of these "core four" cosmetic specialties.

Cameron Chesnut, MD, FAAD, FACMS, FASDS
Spokane Dermatologic Surgeon
5.0 out of 5 stars 6 reviews

Juvéderm Voluma is a wonderful new filler for volume

Juvéderm Voluma became available in December 2013. It's approved for cheek volumizing and is the first hyaluronic acid filler with the FDA approval for that. I'm very impressed with the smooth look and feel of this filler, and the ability to see an instant lift and shaping to the cheeks. Physicians who were involved with the clinical trials for approval and physicians in other countries who have used this product longer are impressed with a duration of results that can be 2 years! 

Radiesse will still have a role to play, but Juvéderm Voluma is an important addition to our treatment options. A distinct advantage that Juvéderm Voluma has is the ability to remove it if desired. 

Kimberly Finder, MD
San Antonio Dermatologic Surgeon
5.0 out of 5 stars 35 reviews

Juvederm Voluma is a great alternative to Radiesse

Personally I like both fillers.  There are advantages and disadvantages to each.  Voluma is an HA product which is good for first time patients since it is reversible.  However, Voluma is slightly more expensive and come with less volume in the syringe, so it ends up costing the patient more to achieve the same result.  However, in the FDA studies, Voluma was shown to last up to 2 years or longer.  Radiesse is not an HA and can't be reversed.  However, is comes with more volume per syringe is is slightly less expensive so the patient gets more for their money in the short-term.  Radiesse is also long lasting and typically lasts longer than other HA products except Voluma.  In terms of results, I have found Voluma to be slightly smoother since these fillers are used for deeper injections, I don't think this is clinically appreciable except during the injection process.  

Good Luck.    

David Shafer, MD
New York Plastic Surgeon
5.0 out of 5 stars 63 reviews

Voluma cheek augmentation

Voluma is a fantastic product for cheek augmentation.  It is the newest kid on the block. There are other traditional fillers that are also excellent candidates for cheek augmentation. These include Perlane, Juvederm and Radiesse.  . What is more important than the type of filler is the experience of the injector. I would definitely recommend going to a board-certified plastic surgeon as they are also qualified at doing procedures such as cheek augmentation using implants or fat grafting. They would be best able to help you understand the pros and cons and the longevity of each different approach.

The one distinction that Voluma has versus the other fillers, is that it is the only FDA approved product for cheek augmentation. However doctors commonly use products for off label reasons.  

Is Juvederm Voluma an Alternative to Radiesse?

Juvederm Voluma is an alternative to Radiesse in that it is a deeper volumizing filler and can be reversed. It is an excellent volumizing filler.

Rod J. Rohrich, MD
Dallas Plastic Surgeon
5.0 out of 5 stars 25 reviews

Voluma is a new and excellent alternative to Radiesse

Voluma (from Juvederm) is newly available in the US, expanding their treatment options.  It is not indicated for filling wrinkles, but rather used to restore the areas of the face that show volume loss.  

Facial aging often includes some degree of loss of fullness in the cheeks (sagging fat and thinning bones).  Traditional treatments include fat grafting and certain refinements of facelift techniques.  Injectable fillers including Radiesse and Sculptra are alternative ways to enhance cheek volume.  Now we have Voluma, the first hyaluronic acid volume filler.  It gives immediate results and is reversible if ever needed.

Sutton Graham II, MD
Greenville Plastic Surgeon
4.5 out of 5 stars 3 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.