Juvederm: Q&A

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Juvederm Ingredients - How is Juvederm Made?

Where does the material in Juvederm come from? I heard that it's natural  - what is it made from?

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8 Doctor Answers | Asked by Mollie
+3

Juvederm is good stuff!

Juvederm is a filler that will soften fine lines and wrinkles. It is made of Hyaluronic acid (HA). HA is a natural occuring component of your skin. 40% of your Dermis (the deep layer) is made from HA and the remainder is made from collagen. HA can be derived from other animals (roosters, pigs) but these forms of HA have unique proteins that can make them more susceptible to an allergic reaction. Juvederm is made from a synthetic process using bacteria. The bacteria are completely removed... more
+3

Juvederm is made from hyaluronic acid

Juvederm is a dermal filler which is made of non-animal stabilized hyaluronic acid. Because hyaluronic acid occurs naturally in the body, no prior allergy test is needed. The product is injected into (or below the dermis) to provide desired augmentation. Thanks for your question! Dr. Stephen Goldstein
+2

Juvederm: A natural component of the skin.

Juvederm is a gel with a smooth consistency that is made of hyaluronic acid. Hyaluronic acid is a naturally occurring substance in your skin that adds volume and hydration, and is quite effective in correcting lines and grooves. The hyaluronic acid in Juvederm is generated by bacterial cultures and is not animal derived. Because hyaluronic acid is a natural component of the skin, there are very few reactions to Juvederm injections.

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+2

Juvederm is hyaluronic acid

Juvederm is a syntetic hyaluronic acid. Hyaluronic acid is a sugar-water molecule that makes up the normal skin’s infrastructure, cushioning the collagen and providing support.
+2

Juvederm is hyaluronic acid

Juvederm Ultra and Ultra Plus are non-animal derived hyaluronic acid (HA) fillers. Juvederm is produced from bacterial fermentation. Hyaluronic acid is identical across species, so no HA filler requires skin testing for allergy. Juvederm results last up to one year, as the filler is gradually broken down by your body. While FDA approved for filling lines around the mouth, it is often used "off-label" for lip enhancement, cheek lifting, and sunken areas under the eyes. Besides... more
+1

Juvederm comes from strep

Juvederm is derived from a bacterial source, streptococcus equi. Don't worry this is a harmless bacteria species to start off with. It is then broken down so the hyaluronic acid part is extracted out. (Back in 1965, I was extracting lipopolysaccharides from E. Coli a truly dangerous bacteria, but the extract was harmless....though we never thought of injecting it into people!). This bacteria-derived hyaluronic acid is also a polysaccharide, a glorified sugar molecule. Since hyaluronic acid has more
+1

From bacterial cultures

Juvederm is just one form of hyaluronic acid filler. Hyaluronic acid  is naturally found in your body.  Juvederm specifically is derived in the laboratory from bacterial cultures.
+1

Juvederm

Juvederm is marketed in the US by Allergan. It is manufactured in France and is derived from Streptococcus bacteria. It is then highly purified. It is not derived in any way from cadaver or animal sources. Its main component is cross-linked hyaluronic acid and is molecularly identical to the hyaluronic acid found naturally in the human body. This is the reason why allergic reactions are very rare, and why its effect is so long lived.
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Comments (4)

I am a cancer survivor. I would like to know if Juvederm has any preservatives in it. Thank you.

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I posted this as a separate Q&A for you since it is unlikely that the doctors will see your comments in this section. Below is a link if you would like to check for answers. It usually takes 24-48 hours for the doctors board certified doctors that volunteer on RealSelf to start sharing their opinions:

Does Juvederm Contain Preservatives?

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If juvederm HA is a naturally occurring substance in animals then WHERE are they getting it from? Is it cows?

  • Reply

Dr. Freund explained this quite well in the information he shared, "HA can be derived from other animals (roosters, pigs) but these forms of HA have unique proteins that can make them more susceptible to an allergic reaction. Juvederm is made from a synthetic process using bacteria.

The bacteria are completely removed at the end of the process and their is no residual protein to cause the allergic reaction."

You can click on "Doctor Answers" above and look for him in the list if you would like to read his full answer.

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These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.

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