Hi Parveen, Hand rejuvenation is best approached with a comprehensive treatment plan that will include prevention, skin care, laser, and dermal fillers. There are a number of options available, depending on the condition of your skin and the desired outcome. The best filler will depend on many factors; also, the best filler for you might not be the best filler for someone else. Filler type can be separated into hyaluronic acid (HA) fillers, which can be reversed, and non-HA fillers, which generally last considerably longer. For first time treatments I like to use HA fillers. Having the reversibility option makes them safer and leaves the option for them to be removed if for some reason the patient doesn't like the result. If your skin is very thin, then a thin filler that has less cross linking and smaller particle size is in order. All major HA producers will have a range of fillers on offer that work well. Please consult with a physician experienced in providing comprehensive treatment plans that include skin care, lasers, and fillers, and plan a long-term strategy that will keep your hands looking youthful and natural. Best of luck!