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Can Botox Injections Be Reversed?

If you have had too much Botox in an area is there an antidote to help release the effects quicker?

Doctor Answers 17

Unfortunately there is no 'antidote' to Botox. In some...

Unfortunately there is no 'antidote' to Botox. In some cases, the effects can be changed - for instance, differences in one side versus another can be lessened with additional Botox treatment.

Care must be taken when administering Botox to start with lower doses and advance as needed to get the effect desired.

Dallas Facial Plastic Surgeon
4.0 out of 5 stars 13 reviews

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The short answer is 'no'. Botox is a powerful neurotoxin...

The short answer is 'no'.

Botox is a powerful neurotoxin that nature designed to bind avidly to other proteins and deactivate them. There is not a reliable antidote for it for cosmetic use.

The fortunate thing about Botox is that is temporary. Certainly this is not a consolation for you, since you're experiencing the adverse effects of Botox: too much paralysis or paralysis in a region that is undesirable.


"Botox reversal" - Time is your best bet

While there are ways to treat some of the side effects of an injector using too much Botox, the best best is generally to wait until the Botox subsides.

To avoid this problem, an experienced injector will be very conservative when treating a new patient. Additional units can be provided much more easily than dealing with the problems of over-injection.

Kris M. Reddy, MD, FACS
West Palm Beach Plastic Surgeon
4.5 out of 5 stars 21 reviews

Over-Botoxed? Time may be your only ally

Rarely the result may not be enough to make you happy. Many physicians are conservative and prefer to not put in too much initially until they see how you react. More units may be administered two to four weeks after to give you a better result. If not enough areas were treated and there is unwanted persistent muscle movement in a specific location of the face, then those areas can be treated subsequently giving you a better result.

If, however, there is a droop of the eyelid when the forehead is treated, a prescription eye drop may be used to give you a little lift of the eyelid. If the forehead is dropped than some more units may be given into the muscles that pull the forehead down, thereby relaxing it up further.

If there is a droop that cannot be treated by the previously mentioned treatments, then time alone will help. A droopy eyelid may look better in three weeks or more.

Ronald Shelton, MD
Manhattan Dermatologist
5.0 out of 5 stars 33 reviews

Reversing Botox effects

Unlike some injectable treatments, the effects of a Botox treatment cannot be reversed. You can either get another treatment performed to "fix" the results or wait it out. Usually, it takes about 4 months or so for the effects to go away, after which your face will look the same as before your treatment.

No Antidote for Botox

There is nothing that will make the effects of Botox go away faster. Unfortunately, the only thing you can do is wait for the effects to wear off. This normally takes about 3 months for the complete resolution of the effects of the product. In the future, you may request that the amount injected be adjusted so that less is injected. The product will not have such a dramatic or long lasting effect if less is injected.

Botox Is Not Permanent & Lasts Usually 3-4 Months

The vast majority of patients who undergo botox injections are extremely satisfied with the results of their procedure. Unfortunately, we occasionally see patients who aren't happy with the changes that have occurred following treatment. Most of these patients are bothered by soft tissue sag when there’s loss of underlying muscle support or loss of facial expression following these injections.

When these situations arise, there's usually no intervention that can reverse the effect of botox. Fortunately botox isn’t permanent. The effect of botox typically takes 3 to 4 months to disappear. In some cases where botox has caused droopy eyelids, prescription eye drops that effect mullers muscle can be used to reverse the impact of botox.

In most cases, waiting until the botox loses its biologic effect is the only option available.  Under these circumstances ,it's important to stay close to your physician. Your physician should be able to help you get through the experience.

Unfortunately, Botox cannot be

Hello Denise,

Unfortunately, Botox cannot be "reversed".  There are eyedrops available that may alleviate certain effects, such as droopy eyelid (albeit via a different mechanism).

Fortunately, though, the toxin "wears off" with time. 



Anand G. Shah, MD
San Antonio Facial Plastic Surgeon
3.5 out of 5 stars 3 reviews

Can Botox Injections Be Reversed

The answer is no. There is no Botox antidote to prevent its actions. If there is too much effect in an area of the face then one will have to wait for 3 – 4 months for the effect to wear off.

Thomas Guillot, MD
Baton Rouge Plastic Surgeon
5.0 out of 5 stars 6 reviews

Botox Injection Wears off with Time

Unfortunately no, there is nothing that can be injected to diminish the effect of Botox. The good news is that it only takes time. By the time the standard four months is up any trace of the Botox will have been metabolized and the area should go back to its normal state.  It is dose dependent so if a small amount is used then is will diminish quicker.



Edward E. Dickerson, IV, MD
Fayetteville Facial Plastic Surgeon
4.5 out of 5 stars 61 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.