Botox to Correct Wrinkled Eyelid?

Thank you for the question.

The area you described generally does not  respond well to Botox injection. It may actually cause drooping of the eyebrows or eyelids.

Best wishes.

If your vertical crease is extending from the eyelash part of the eyelid, or slightly higher, upwards to the eyebrow, then you probably will not obtain benefit from Botox injections at the crow's feet (outer eyelid) and Botox can cause a significant drop of the upper eyelid if injected in the area of your vertical crease! This drop can last more than three months.  See a board-certified dermatologist, plastic surgeon, or oculoplastic surgeon for a consultation to determine what other treatments may help.

The type of crease you describe is more likely due to a depletion of collagen and elastin rather than chronic muscle movements.  Neither Botox nor surgery will build collagen, and the location of your crease is not suitable for filler, so I recommend fractionated CO2 laser resurfacing with Total FX.