Hi Curiousco,
If you are contemplating having both fillers and Fraxel re:pair, it is best to have the laser treatment first. There have not been definitive studies to show the effect of Fraxel re:pair on Restylane, but one would think that the heat of the laser may cause the filler to possibly break down faster. Additionally, the laser treatment stimulates the patient's own collagen production, stimulating increased volume so that less filler will be needed after the treatment.
Sculptra is not effected by the laser as it is placed deeper below the skin.
Good luck and be well.
Dr. P



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