Tiny bumps on the nose can be frustrating because several different skin conditions can look very similar, and each one is treated differently. From your description, especially since a month of isotretinoin didn't improve them and microneedling with radiofrequency worsened the scarring, it's important to identify exactly what these bumps are before pursuing additional procedures. Some of the more common possibilities include: Sebaceous hyperplasia (enlarged oil glands) Sebaceous filaments, which are normal but can appear more prominent Closed comedones (whiteheads) Milia Less commonly, conditions such as fibrous papules or other benign growths If these bumps are related to enlarged oil glands or sebaceous filaments, isotretinoin may help reduce oil production over time, but one month is generally too short to judge its full effect. Improvements, when they occur, often require several months of treatment. Because you've noticed increased scarring after RF microneedling, I would be cautious about repeating aggressive resurfacing procedures until the diagnosis is clear. Continuing treatments that irritate the area without addressing the underlying cause may lead to more textural changes rather than improvement. Depending on the diagnosis, treatment options may include: Topical retinoids (if appropriate) Professional comedone extraction Electrocautery or laser treatment for sebaceous hyperplasia Chemical peels for clogged pores Observation if they represent normal sebaceous filaments My recommendation would be to focus first on obtaining an accurate diagnosis rather than trying additional procedures. Once the exact cause is identified, treatment can be tailored much more effectively and with a lower risk of additional scarring.Tiny bumps on the nose can be frustrating because several different skin conditions can look very similar, and each one is treated differently. From your description, especially since a month of isotretinoin didn't improve them and microneedling with radiofrequency worsened the scarring, it's important to identify exactly what these bumps are before pursuing additional procedures. Some of the more common possibilities include: Sebaceous hyperplasia (enlarged oil glands) Sebaceous filaments, which are normal but can appear more prominent Closed comedones (whiteheads) Milia Less commonly, conditions such as fibrous papules or other benign growths If these bumps are related to enlarged oil glands or sebaceous filaments, isotretinoin may help reduce oil production over time, but one month is generally too short to judge its full effect. Improvements, when they occur, often require several months of treatment. Because you've noticed increased scarring after RF microneedling, I would be cautious about repeating aggressive resurfacing procedures until the diagnosis is clear. Continuing treatments that irritate the area without addressing the underlying cause may lead to more textural changes rather than improvement. Depending on the diagnosis, treatment options may include: Topical retinoids (if appropriate) Professional comedone extraction Electrocautery or laser treatment for sebaceous hyperplasia Chemical peels for clogged pores Observation if they represent normal sebaceous filaments My recommendation would be to focus first on obtaining an accurate diagnosis rather than trying additional procedures. Once the exact cause is identified, treatment can be tailored much more effectively and with a lower risk of additional scarring.