Does hylauronidase dissolve HA filler evenly? (photos)

Question

I've been injecting HA for 5 years and everything was perfect until last time. The doctor injected the filler in the wrong place and it migrated up north, almost to the nose, making my upper lip look asymmetric and thin (although there's a lot of filler inside). So The only option now is hylauronidase, but I'm afraid to inject it, since I've read some scary reviews about it leaving hollow patches in the skin (especially when there're leftovers of old injections). So, is hylauronidase safe?

Raffy Karamanoukian, MD, FACS · Answer

Our office specializes in hyaluronidase injections to reverse facial fillers. This injection should only be injected by experts in its use and application. It dissolves the filler where injected. Best, Dr. Karamanoukian Los Angeles

Brian S. Biesman, MD · Answer

I am sorry that you did not obtain satisfactory results from your injection.  While hyaluronidase can remove all of the filler present if injected in large enough dose and concentration, with smaller, more dilute solutions a lesser effect can often be achieved.  This is not an easy, readily predictable procedure (e.g. where 10% or 20%) of the HA can be reduced but, in my personal experience, there can be a middle ground between all and nothing.  I recommend finding an injector who is extremely experienced with hyaluronidase.

J. Jason Wendel, MD, FACS · Answer

Thank you for your question.It can be very difficult to control the amount of filler that is dissolved by hyaluronidase...very difficult.  It may result in more uneven lips.

To be sure, see two or more board-certified providers in
your area for a complete evaluation to make sure you are a good candidate and
that it is safe for you to have these treatments.

I hope this helps.

Stephen Weber MD, FACS · Answer

If hyaluronidase is injected properly in the correct amount, it works very evenly and shouldn't result in any divots or contour issues. I always recommend very conservative injections with followup scheduled about one week later. This allows for more precise dissolution of the filler and avoids any unexpected results. I hope this information is helpful for you.Stephen Weber MD, FACSDenver Facial Plastic Surgeon

Harold J. Kaplan, MD · Answer

Hi SweetMint.  Hyaluronidase is very safe although we do use a patch test to determine if patients are allergic before we use it.  Hyaluronidase does not dissolve the regular skin tissue , rather it only works to dissolve the Hyaluronic acid based product like Restylane, Juvederm, Perlane, Belotero and Voluma.  If your filler was placed evenly, it will dissolve it evenly.  Good luck.

Does hylauronidase dissolve HA filler evenly? (photos)

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Does hylauronidase dissolve HA filler evenly? (photos)

Answers (6)

Answer: Does hylauronidase dissolve dermal filler evenly?

Answer: Does hylauronidase dissolve dermal filler evenly?

Answer: Hyaluronidase is Safe

Answer: Hyaluronidase is Safe

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Recommended reading

Everything you need to know about Hyaluronidase

Our mission is to create a world where every investment in modern beauty is Worth It.